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Article: Differential changes of potassium currents in CA1 pyramidal neurons after transient forebrain ischemia.

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Chi XX; Xu ZC
J. Neurophysiol., 2000


Table 4.

Kinetics of delayed rectifier potassium current before and after ischemia

Control 6–8 h 12–14 h 18–20 h 36 h
V 1/2 (Act), mV −4.95 ± 1.92 −8.10 ± 2.26 −1.80 ± 2.63 −3.12 ± 2.03 −16.36 ± 1.64*
V c (Act), mV 21.33 ± 1.44 21.51 ± 1.73 24.16 ± 1.84 22.35 ± 1.48 19.08 ± 1.34
V 1/2 (Inact), mV −63.44 ± 1.36 −66.67 ± 1.20 −65.29 ± 1.46 −65.09 ± 2.23 −71.08 ± 1.20
V c (Inact), mV 22.52 ± 1.26 21.15 ± 1.10 21.49 ± 1.35 23.75 ± 2.10 22.98 ± 1.11

  • V 1/2, the potential of half-maximal activation or inactivation; V c, proportional to the slope at V 1/2; * P < 0.05.


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