Table 1. Activation parameters for recombinant HCN channels and native Ih
| Channel | V1/2 (mV) | z (eq.) | n |
|---|---|---|---|
| Peak tail currents of recordings similar to those depicted in Fig. 1C were baseline subtracted and a Boltzmann function was fitted to the data (eqn (1), see Methods). *P < 0.05 when comparing to the CS-TG data with Student's t test. | |||
| CS-TG | −90.0 ± 2.1 | −3.1 ± 0.2 | 15 |
| HCN1 | −79.1 ± 2.1 (*) | −4.3 ± 0.4 | 5 |
| HCN1/HCN2 | −85.3 ± 1.4 | −3.9 ± 0.4 | 7 |
| HCN2 | −98.4 ± 1.9 (*) | −3.9 ± 0.6 | 6 |
| HCN4 | −79.1 ± 2.6 (*) | −2.3 ± 0.2 (*) | 4 |