Cell Type | |||||
---|---|---|---|---|---|
1 | 2 | 3 | 4 | 7 | |
n | 28 | 22 | 21 | 24 | 8 |
Cell properties | |||||
Diameter, μm | 24–30 | 25–32 | 18–22 | 33–40 | 16–22 |
Size, pF | 31.4 ± 1.1 | 31.5 ± 0.8 | 21.2 ± 1.3 | 56.8 ± 1.9 | 18.2 ± 1.3 |
Input Resistance, MΩ | 604.5 ± 57.6 | 726.7 ± 49.2 | 544.9 ± 66.9 | 297.1 ± 23.6 | 811.7 ± 127.4 |
Membrane potential, mV | −56.0 ± 0.4 | −57.2 ± 0.7 | −51.7 ± 1.3 | −58.0 ± 1.0 | −48.4 ± 1.9 |
Peak current | |||||
Capsaicin, pA/pF | 25.9 ± 6.6 | 134.9 ± 16.32-a | 0.0 | 0.4 ± 0.1 | 4.25 ± 0.9 |
Protons, pA/pF | 5.6 ± 2.4 | 15.3 ± 2.72-b | 127.0 ± 16.0 | 3.48 ± 0.4 | 45.8 ± 18.12-l |
ATP, pA/pF | 13.3 ± 3.82-c * | 51.7 ± 10.1 | 0.0 | 17.4 ± 3.5 | 2.9 ± 0.4 |
αβ-methylene-ATP, pA/pF | No test | 44.6 ± 10.3 | 0.0 | 1.6 ± 0.5 | No test |
Action potential | |||||
Duration, ms | 7.35 ± 0.52-d | 5.9 ± 0.12-e | 3.5 ± 0.22-f | 3.1 ± 0.12-g | 6.5 ± 0.22-h |
Afterhyperpolarization, ms | 57.0 ± 8.12-k | 54.7 ± 7.62-k | 17.5 ± 1.72-i | 46.5 ± 5.52-k | 110.2 ± 9.82-j |
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Values are means ± SE. Cell body properties, peak currents, and action potential features of subclassified cells are presented. The cases represent only those in which ATP, capsaicin, and protons were presented to the same cell. The order of presentation was counterbalanced. αβ-methylene-ATP was presented in a limited number of additional cases (type 2, n = 8; type 4,n = 5).
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↵F2-a Significantly greater than all other cells.
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↵F2-b Significantly greater than type 1.
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↵F2-c Significantly greater than type 4.
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↵F2-d Significantly greater than all other cells.
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↵F2-e Significantly greater than types 3 and 4.
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↵F2-f Significantly less than types 1, 2, and 7.
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↵F2-g Significantly less than types 1, 2, and 7.
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↵F2-h Significantly greater than types 3 and 4.
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↵F2-i Significantly less than all other cells.
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↵F2-j Significantly greater than all other cells.
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↵F2-k Significantly greater than type 3 and significantly less than type 7.
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↵F2-l Approached significance vs. type 3,P < 0.10. Statistics and probabilities are presented in the text. For protons and ATP-activated currents, statistical comparisons were only made between currents of similar form (i.e., desensitizing or non-desensitizing). * n = 6.