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Article: Cannabinoid receptors in the bed nucleus of the stria terminalis control cortical excitation of midbrain dopamine cells in vivo.

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Massi L; Elezgarai I; Puente N; Reguero L; Grandes P; Manzoni OJ; Georges F
J. Neurosci., 2008


Table 2.

Percentage of presynaptic and postsynaptic elements immunoreactive for CB1-R in the BNST after injection of the anterograde tracer (PHA-L) in the prefrontal cortex and the retrograde tracer (CTb) in the mesencephalon

Tracers Profile Percentage of CB1 positives profiles No. of particles per μ m ±SEM Total no. of profiles Percentage of total particles distribution
PHA-L Presynaptic (terminals) 92.68 1.13 + 0.13 86 73.83 (membrane) 26.17 (cytoplasm)
CTb Synaptic contact (terminals ± dendrites) 77.15 0.74 + 0.05 83 70.74 (membrane) 29.86 (cytoplasm)

  • The percentage of CB1-R-labeled presynaptic and postsynaptic compartments relative to PHA-L and postsynaptic CTb is shown. Note that the vast majority of infralimbic terminals within the BNST have the CB1-R. BNST sections used for counting were obtained from four rats. Electron micrographs were taken at a final magnification of 15,000×.


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