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Article: Molecular and physiological diversity of nicotinic acetylcholine receptors in the midbrain dopaminergic nuclei.

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Klink R; de Kerchove d'Exaerde A; Zoli M; Changeux JP
J. Neurosci., 2001


Table 4.

ACh-elicited current waveform parameters in DA neurons of WT and α4 −/− mice

WT (n = 8) α4 −/− (n = 15)
Amplitude 132  ± 26 pA 72  ± 7 pA4-160
Rise time 242  ± 38 msec 96  ± 17 msec4-160
Decay T 1/2 562  ± 66 msec 316  ± 47 msec4-160
  • Decay T 1/2 was the time measured between peak and half maximal amplitude.

  • F4-160 p < 0.01.


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