Table 1.
Physiological properties of neurons in the hilus and fascia dentata of the hippocampal formation
| Cell Type | n* | Resting Potential, mV | RN, MΩ | τ0, ms | Sag Ratio | Maximum Firing Rate, s−1 | Spike Width, ms | Fast AHP, mV | Slow AHP, mV |
|---|---|---|---|---|---|---|---|---|---|
| Granule cells | 16 (16) | −75 ± 2 | 292 ± 34 | 31 ± 2 | 0.97 ± 0.01 | 72 ± 8 | 0.87 ± 0.06 | −11.7 ± 1.1 | −0.6 ± 0.4 |
| −86, −60 | 111, 650 | 16, 43 | 0.93, 1.02 | 39, 128 | 0.53, 1.48 | −22.5, −3.4 | −2.6, 1.2 | ||
| Basket cells | 3 (3) | −62 ± 3 | 43 ± 5 | 10 ± 1 | 0.97 ± 0.02 | 230 ± 15 | 0.25 ± 0.04 | −20 ± 2.3 | −2.3 ± 0.2 |
| −66, −56 | 32, 54 | 9, 11 | 0.91, 1.00 | 212, 266 | 0.18, 0.33 | −24.9, −14.9 | −2.8, −1.9 | ||
| Mossy cells | 9 (8) | −62 ± 1 | 199 ± 19 | 41 ± 3 | 0.81 ± 0.03 | 50 ± 6 | 0.78 ± 0.04 | −6.2 ± 0.9 | −2.8 ± 0.7 |
| −67, −55 | 83, 287 | 24, 52 | 0.66, 0.91 | 33, 83 | 0.53, 0.96 | −11.8, −2.9 | −6.0, 0.7 | ||
| Spiny interneurons | 3 (2) | −65 ± 6 | 371 ± 47 | 35 ± 0 | 0.82 ± 0.02 | 69 ± 4 | 0.72 ± 0.08 | −13.1 ± 3.0 | −3.1 ± 1.0 |
| −75, −50 | 286, 480 | 35, 35 | 0.78, 0.86 | 61, 77 | 0.53, 0.87 | −20.0, −7.2 | −5.2, −1.1 | ||
| IML aspiny interneurons | 4 (4) | −64 ± 2 | 363 ± 62 | 30 ± 6 | 0.80 ± 0.04 | 81 ± 9 | 0.50 ± 0.02 | −12.3 ± 2.3 | −9. ± 2.7 |
| −68, −59 | 194, 516 | 11, 41 | 0.68, 0.89 | 58, 108 | 0.44, 0.55 | −18.7, −6.0 | −14.7, −1.3 | ||
| OML aspiny interneurons | 2 (1) | −68 ± 2 | 284 ± 89 | 15 | 0.84 ± 0.06 | 101 ± 24 | 0.62 ± 0.18 | −16.8 ± 1.8 | −7.5 ± 4.6 |
| −70, −65 | 158, 410 | 15 | 0.76, 0.92 | 66, 135 | 0.37, 0.87 | −19.4, −14.2 | −14.0, −0.9 |
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For each parameter, mean ± SD and range (low, high) are indicated. IML and OML, inner and outer molecular layer.
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↵* The n value for τ0 is indicated in parentheses; see Methods for explanation.