Spike-wave discharges are defined as three or more single spikes scored within the period of 1 s. Mean ± SD of amplitude (Amp),
frequencies (Fr), and duration (in seconds) of the discharges are displayed. Frequencies are defined as the average occurrence
of discharges per hour. The baseline of EEG in BACE1-null mice was ∼50 μV, whereas that of wild-type mice was ∼20 μV.