Postsynaptic potentials (PSPs) evoked in motoneurons by stimulation of the L5 dorsal root; threshold for PSP production (< 1.3 x T); threshold for orthodromic action potential generation (between 1.3 x T and 5 x T). *P = 0.035, permutation with general scores test. Values are median ± quartile (with range in parentheses). WT, wild-type.
Article: Early electrophysiological abnormalities in lumbar motoneurons in a transgenic mouse model of amyotrophic lateral sclerosis.
Full Text (publisher's website) ; Article Metadata ; Article Data (extracted) Bories C; Amendola J; Lamotte d'Incamps B; Durand J Eur. J. Neurosci., 2007
Low stimulus intensity (< 1.3 × T) | 1.3 × T < stimulus intensity < 5 × T | |||
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WT | SOD1G85R | WT | SOD1G85R | |
Amplitude (mV) | 5.95 ± 1.3 (3.4–15) | 4.2 ± 1.9 (1.56–13.6) | 18 ± 3 (7.5–25) | 15.2 ± 5.4 (6.2–21)* |
Time to peak (ms) | 4.4 ± 4.6 (1.6–27) | 6.2 ± 3.1 (1.6–25) | 5.3 ± 2.5 (1.46–28) | 3.3 ± 1.4 (1.44–35.7) |
Half-width (ms) | 31 ± 27 (4.6–114) | 21 ± 15 (6.45–154) | 90 ± 40 (5.8–213) | 57 ± 15 (7.4–950) |
Duration (ms) | 165 ± 113 (55–2000) | 93 ± 66 (40–2900) | 1200 ± 486 (120–2500) | 915 ± 1101 (120–9000) |
Motoneurons (n) | (22) | (18) | (17) | (16) |
Inferred neuron-electrophysiology data values
Neuron Type | Neuron Description | Ephys Prop | Extracted Value | Standardized Value | Content Source |
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