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Article: Early electrophysiological abnormalities in lumbar motoneurons in a transgenic mouse model of amyotrophic lateral sclerosis.

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Bories C; Amendola J; Lamotte d'Incamps B; Durand J
Eur. J. Neurosci., 2007


Table 2.   Dorsal root-evoked synaptic potential characteristics
 Low stimulus intensity (< 1.3 × T)1.3 × T < stimulus intensity < 5 × T
WTSOD1G85RWTSOD1G85R
  1. Postsynaptic potentials (PSPs) evoked in motoneurons by stimulation of the L5 dorsal root; threshold for PSP production (< 1.3 x T); threshold for orthodromic action potential generation (between 1.3 x T and 5 x T). *P = 0.035, permutation with general scores test. Values are median ± quartile (with range in parentheses). WT, wild-type.

Amplitude (mV)5.95 ± 1.3 (3.4–15)4.2 ± 1.9 (1.56–13.6)18 ± 3 (7.5–25)15.2 ± 5.4 (6.2–21)*
Time to peak (ms)4.4 ± 4.6 (1.6–27)6.2 ± 3.1 (1.6–25)5.3 ± 2.5 (1.46–28)3.3 ± 1.4 (1.44–35.7)
Half-width (ms)31 ± 27 (4.6–114)21 ± 15 (6.45–154)90 ± 40 (5.8–213)57 ± 15 (7.4–950)
Duration (ms)165 ± 113 (55–2000)93 ± 66 (40–2900)1200 ± 486 (120–2500)915 ± 1101 (120–9000)
Motoneurons (n)(22)(18)(17)(16)

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Inferred neuron-electrophysiology data values

Neuron Type Neuron Description Ephys Prop Extracted Value Standardized Value Content Source