Membrane properties of granule cells recorded in normal artificial cerebrospinal fluid with patch electrodes containing K+-methyl sulfate. No significant differences were noted in the membrane properties of granule cells from aged versus adult Fischer 344 rats. Comparisons were performed between cells/groups as well as animals/group. The data here and in the following table are expressed as mean ± SEM AP amp., action potential amplitude; Rin, input resistance; Vm, membrane potential.
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Article: Dentate filter function is altered in a proepileptic fashion during aging.
Full Text (publisher's website) ; Article Metadata ; Article Data (extracted) Patrylo PR; Tyagi I; Willingham AL; Lee S; Williamson A Epilepsia, 2007
| By cell Group | No. of cells | Rin (MΩ) | Vm (mV) | AP amp (mV) | Spike width (ms) | Time constant (ms) |
|---|---|---|---|---|---|---|
| Adult | 22 | 166.2 ± 10.2 | −74.9 ± 1.7 | 93.8 ± 2.8 | 1.1 ± 0.04 | 20.8 ± 1.5 |
| Aged | 28 | 186.8 ± 12.6 | −71.4 ± 1.2 | 89.5 ± 2.8 | 1.2 ± 0.05 | 18.4 ± 0.9 |
| By animal | ||||||
| Group | No. of animals | Rin (MΩ) | Vm (mV) | AP amp (mV) | Spike width (ms) | Time constant (ms) |
| Adult | 10 | 170.1 ± 14.2 | −72.2 ± 2.8 | 93.2 ± 3.5 | 1.1 ± 0.04 | 20.8 ± 2.1 |
| Aged | 14 | 181.1 ± 16.4 | −71.5 ± 1.2 | 90.3 ± 3.7 | 1.2 ± 0.06 | 18.9 ± 1.1 |