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Article: Evidence from computer simulations for alterations in the membrane biophysical properties and dendritic processing of synaptic inputs in mutant superoxide dismutase-1 motoneurons.
Full Text (publisher's website) ; Article Metadata ; Article Data (extracted) Elbasiouny SM; Amendola J; Durand J; Heckman CJ J. Neurosci., 2010
Table 2.
Summary of metrical parameters of mSOD1-like (morph) morphologies
| Property | Morphologies of mSOD1-like (morph) models | Experimental dataa Mean (confidence interval) | |||||||
|---|---|---|---|---|---|---|---|---|---|
| MN 1 | MN 2 | MN 3 | MN 4 | MN 5 | MN 6 | MN 7 | MN 8 | ||
| Total dendritic path length | 170% | 196% | 165% | 158% | 163% | 146% | 158% | 154% | 165%** (133–197%) |
| Total dendritic membrane area | 186% | 252% | 172% | 149% | 177% | 145% | 177% | 169% | 158%* (125–191%) |
| Total branching points | 265% | 218% | 207% | 191% | 193% | 189% | 179% | 172% | 197%*** (165–229%) |
| Total terminations | 243% | 208% | 195% | 182% | 184% | 178% | 172% | 168% | 189%*** (160–219%) |
| Maximum branch order | 100% | 114% | 111% | 113% | 125% | 113% | 113% | 111% | 137%** (107–167%) |
| Longest dendritic path | 112% | 151% | 119% | 118% | 145% | 100% | 147% | 117% | 105% (88–122%) |
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↵amSOD1 experimental data are presented as percentage of the mean value of the WT measurements. Experimental data are from Amendola and Durand (2008). The 95% confidence interval was computed as mean ± 1.96 × SD/
,
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↵*p < 0.05;
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↵**p < 0.01;
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↵***p < 0.001; ns, not statistically significant.
Inferred neuron-electrophysiology data values
| Neuron Type | Neuron Description | Ephys Prop | Extracted Value | Standardized Value | Content Source |
|---|