No differences in membrane properties of ventral CA1, dorsal CA1, and CA3 pyramidal neurons were observed between controls and after inhibitory avoidance learning or context-only exposure to the IA apparatus. Input resistance, sag, resting potential, spike width, and action potential amplitude values represent means ± SEM.
Article: Learning-dependent plasticity of hippocampal CA1 pyramidal neuron postburst afterhyperpolarizations and increased excitability after inhibitory avoidance learning depend upon basolateral amygdala inputs.
Full Text (publisher's website) ; Article Metadata ; Article Data (extracted) Farmer GE; Thompson LT Hippocampus, 2012
Rats | Cells | Input resistance | Sag | Resting potential | Spike width | AP amplitude | |
---|---|---|---|---|---|---|---|
(n) | (n) | (MΩ) | (mV) | (mV) | (mV) | (mV) | |
CA1v | |||||||
Control | 19 | 29 | 35.5 ± 1.9 | 6.2 ± 0.4 | −66.8 ± 0.9 | 1.3 ± 0.02 | 86.0 ± 1.2 |
Context 1 h | 18 | 25 | 37.5 ± 2.1 | 5.6 ± 0.5 | −66.9 ± 1.3 | 1.3 ± 0.02 | 85.2 ± 0.8 |
Context 24 h | 4 | 11 | 31.6 ± 2.3 | 6.4 ± 0.7 | −66.9 ± 1.3 | 1.4 ± 0.01 | 88.1 ± 0.6 |
Trained 1 h | 22 | 32 | 41.0 ± 1.9 | 6.2 ± 0.4 | −65.4 ± 0.9 | 1.3 ± 0.02 | 84.5 ± 0.8 |
Trained 24 h | 5 | 14 | 41.8 ± 1.6 | 5.7 ± 0.6 | −66.7 ± 1.2 | 1.4 ± 0.02 | 84.4 ± .08 |
Trained > 72 h | 2 | 5 | 44.3 ± 3.4 | 5.7 ± 1.2 | −65.6 ± 3.5 | 1.3 ± 0.06 | 84.8 ± 1.4 |
CA1d | |||||||
Control | 8 | 12 | 40.9 ± 1.5 | 8.3 ± 0.5 | −65.6 ± 1.6 | 1.2 ± 0.02 | 83.0 ± 2.5 |
Context 1 h | 8 | 19 | 35.3 ± 1.9 | 7.3 ± 0.4 | −67.0 ± 0.6 | 1.2 ± 0.02 | 83.6 ± 0.7 |
Context 24 h | 4 | 9 | 41.8 ± 2.4 | 9.0 ± 0.6 | −68.5 ± 1.3 | 1.2 ± 0.01 | 88.0 ± 1.0 |
Trained 1 h | 9 | 15 | 37.5 ± 2.2 | 8.3 ± 0.6 | −65.9 ± 1.2 | 1.3 ± 0.02 | 86.0 ± 1.0 |
Trained 24 h | 6 | 14 | 36.7 ± 2.8 | 9.4 ± 0.7 | −66.7 ± 1.0 | 1.3 ± 0.01 | 88.2 ± 0.8 |
Trained > 72 h | 3 | 6 | 41.2 ± 3.1 | 9.8 ± 0.8 | −65.5 ± 2.6 | 1.3 ± 0.02 | 87.3 ± 1.0 |
CA3 | |||||||
Control | 15 | 21 | 46.6 ± 2.5 | 4.9 ± 0.5 | −67.0 ± 0.8 | 1.2 ± 0.02 | 81.7 ± 1.1 |
Context 1 h | 18 | 20 | 47.5 ± 2.9 | 3.4 ± 0.5 | −68.8 ± 1.1 | 1.2 ± 0.02 | 85.8 ± 0.5 |
Context 24 h | 7 | 9 | 66.0 ± 5.8 | 2.5 ± 1.2 | −67.1 ± 1.8 | 1.3 ± 0.03 | 87.7 ± 0.8 |
Trained 1 h | 17 | 24 | 53.5 ± 2.4 | 4.4 ± 0.5 | −68.1 ± 1.4 | 1.1 ± 0.03 | 82.2 ± 1.6 |
Trained 24 h | 12 | 19 | 43.9 ± 4.3 | 5.7 ± 0.9 | −68.5 ± 1.3 | 1.3 ± 0.01 | 85.1 ± 0.9 |