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Article: Spontaneous bursting activity in the developing entorhinal cortex.
Full Text (publisher's website) ; Article Metadata ; Article Data (extracted) Sheroziya MG; von Bohlen Und Halbach O; Unsicker K; Egorov AV J. Neurosci., 2009
Quantitative parameters of the prolonged intrinsic bursting activity at different postnatal periods
| Parameter (mEC LIII) | 2 mm [Ca2+]o | 1 mm [Ca2+]o | |||||
|---|---|---|---|---|---|---|---|
| P5–P7 | Versus | P5–P7 | Versus | P8–P10 | Versus | P11–P13 | |
| Number of bursts per minute | 2.4 ± 1.8 (n = 7) | ns | 2.9 ± 1.2 (n = 14) | *** | 6.4 ± 3.5 (n = 19) | ns | 8.1 ± 2.3 (n = 10) |
| Burst duration (s) | 11.9 ± 7.4 (n = 7) | ns | 9.9 ± 6.5 (n = 14) | *** | 2.9 ± 1.4 (n = 19) | ns | 2.5 ± 1.2 (n = 10) |
| Interburst interval (s) | 24.3 ± 15 (n = 7) | ns | 17.7 ± 10.5 (n = 14) | * | 9.8 ± 6.6 (n = 19) | ns | 6.1 ± 3.6 (n = 10) |
| Burst amplitude (mV) | 5.7 ± 2.2 (n = 7) | *** | 10.3 ± 2.9 (n = 14) | ns | 12 ± 2.4 (n = 19) | ns | 10.7 ± 4.2 (n = 10) |
| Spike frequency within bursts (Hz) | 2.1 ± 0.5 (n = 7) | *** | 4.7 ± 1.7 (n = 14) | *** | 10.9 ± 6 (n = 19) | ns | 9 ± 4.9 (n = 10) |
| Number of spikes per burst | 23 ± 12 (n = 7) | * | 47 ± 46 (n = 14) | ns | 32 ± 26 (n = 19) | ns | 22 ± 16 (n = 10) |
| Spike threshold (mV) | −44.4 ± 2.7 (n = 7) | ns | −41.3 ± 3.4 (n = 10) | ** | −47 ± 4.3 (n = 14) | ** | −53 ± 4 (n = 8) |
| AHP amplitude (mV) | 2.6 ± 0.5 (n = 3) | ns | 3.6 ± 1.2 (n = 8) | ns | 3.8 ± 1.4 (n = 18) | ns | 3.8 ± 1.5 (n = 7) |
| AHP duration (s) | 17.5 ± 3.5 (n = 3) | ns | 18.8 ± 17 (n = 8) | *** | 4.6 ± 3.6 (n = 18) | ns | 3.4 ± 2 (n = 7) |
| Input resistance (GOhm) | 1.2 ± 0.1 (n = 4) | ns | 1.2 ± 0.3 (n = 11) | *** | 0.6 ± 0.1 (n = 8) | *** | 0.4 ± 0.06 (n = 6) |
| Recording membrane potential (mV) | −60 ± 2.5 (n = 7) | ns | −60.5 ± 1.3 (n = 14) | ns | −62 ± 2.6 (n = 19) | ns | −63 ± 2.5 (n = 10) |
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Averaged data are given as mean ± SD. Recordings were made in ACSF containing 2 mm or 1 mm Ca2+ as indicated on the top. iGluRs and GABAARs were blocked as detailed in Materials and Methods. Unpaired two-tailed t test or Mann–Whitney rank sum test (versus, i.e., left versus right) values are indicated as follows:
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↵*p < 0.05,
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↵**p < 0.01,
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↵***p < 0.005. ns, Not significant.
Inferred neuron-electrophysiology data values
| Neuron Type | Neuron Description | Ephys Prop | Extracted Value | Standardized Value | Content Source |
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