Article: Secondhand smoke exposure alters K+ channel function and intrinsic cell excitability in a subset of second-order airway neurons in the nucleus tractus solitarius of young guinea pigs.

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Sekizawa S; Joad JP; Pinkerton KE; Bonham AC
Eur. J. Neurosci., 2010

Table 1. Comparing intrinsic RS neuron properties in FA-exposed and SHS-exposed animals
	FA	SHS	P-value
V_m, resting membrane potentials; R_in, input resistance; τ, membrane time constant; C_m, cell capacitance; AP thr., action potential threshold; AP peak, peak action potentials from the baseline (−50 mV).
V_m (mV)	−47.6 ± 1.9 (n = 17)	−42.7 ± 2.0 (n = 17)	0.047
R_in (MΩ)	141.7 ± 18.4 (n = 17)	161.2 ± 34.2 (n = 17)	0.310
τ (ms)	9.0 ± 1.1 (n = 17)	10.2 ± 1.4 (n = 17)	0.251
C_m (pF)	69.6 ± 7.4 (n = 17)	93.1 ± 18.6 (n = 17)	0.125
AP thr. (mV)	−42.3 ± 1.2 (n = 17)	−43.3 ± 0.9 (n = 17)	0.239
AP peak (mV)	83.7 ± 4.5 (n = 17)	89.2 ± 5.4 (n = 17)	0.217

Inferred neuron-electrophysiology data values

Neuron Type	Ephys Prop	Extracted Value	Standardized Value	Content Source
Nucleus of the solitary tract principal cell	membrane time constant (ms)	9.0 ± 1.1 (17)	9.0 (ms)	Data Table
Nucleus of the solitary tract principal cell	cell capacitance (pF)	69.6 ± 7.4 (17)	69.6 (pF)	Data Table
Nucleus of the solitary tract principal cell	spike threshold (mV)	-42.3 ± 1.2 (17)	-42.3 (mV)	Data Table
Nucleus of the solitary tract principal cell	spike amplitude from resting (mV)	83.7 ± 4.5 (17)	83.7 (mV)	Data Table
Nucleus of the solitary tract principal cell	resting membrane potential (mV)	-47.6 ± 1.9 (17)	-47.6 (mV)	Data Table
Nucleus of the solitary tract principal cell	input resistance (MΩ)	141.7 ± 18.4 (17)	141.7 (MΩ)	Data Table