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Article: Differential GABAA receptor clustering determines GABA synapse plasticity in rat oxytocin neurons around parturition and the onset of lactation.

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Koksma JJ; Fritschy JM; Mack V; Van Kesteren RE; Brussaard AB
Mol. Cell. Neurosci., 2005


Table 1Pipette, membrane and action potential characteristics for neurons in the DMH either retrogradely labeled with DiI injected into the PVN (DiI+) or unlabeled (DiI−)
ParameterDiI− (n=54)DiI+ (n=32)
Resting membrane potential (RMP, mV)−60.1±1.0−59.6±1.2
Action potential peak (mV)8.8±1.09.6±1.2
After hyperpolarizing after-potential (AHAP, mV)−5.6±0.8−3.5±0.7
Amplitude RMP to peak (AmRMP, mV)68.8±1.669.2±1.4
Amplitude threshold to peak (AmTHR, mV)48.7±1.246.9±1.2
Threshold (THR, mV)−39.9±0.7−37.3±1.0*
Duration (DUR, ms)1.2±0.11.3±0.1
Pipette resistance (Rp, MΩ)3.8±0.13.9±0.2
Series resistance (Rs, MΩ)9.3±0.39.2±0.3
Membrane time constant (Tau, ms)24.1±1.223.1±1.2
Input resistance (Ri, MΩ)698±37655±39
*Significant difference (P<0.05) between labeled and unlabeled neurons compared with ANOVA and Fisher’s PLSD post-hoc analysis.

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Inferred neuron-electrophysiology data values

Neuron Type Neuron Description Ephys Prop Extracted Value Standardized Value Content Source
Hypothalamus oxytocin neuroendocrine magnocellular cell other -5.6 ± 0.8 -5.6 (None) Data Table
Hypothalamus oxytocin neuroendocrine magnocellular cell spike amplitude 48.7 ± 1.2 48.7 (mV) Data Table
Hypothalamus oxytocin neuroendocrine magnocellular cell spike threshold -39.9 ± 0.7 -39.9 (mV) Data Table
Hypothalamus oxytocin neuroendocrine magnocellular cell spike width 1.2 ± 0.1 1.2 (ms) Data Table
Hypothalamus oxytocin neuroendocrine magnocellular cell other 3.8 ± 0.1 3.8 (None) Data Table
Hypothalamus oxytocin neuroendocrine magnocellular cell access resistance 9.3 ± 0.3 9.3 (MΩ) Data Table
Hypothalamus oxytocin neuroendocrine magnocellular cell membrane time constant 24.1 ± 1.2 24.1 (ms) Data Table
Hypothalamus oxytocin neuroendocrine magnocellular cell input resistance 698.0 ± 37.0 698.0 (MΩ) Data Table
Hypothalamus oxytocin neuroendocrine magnocellular cell resting membrane potential -60.1 ± 1.0 -60.1 (mV) Data Table
Hypothalamus oxytocin neuroendocrine magnocellular cell spike peak (mV) 8.8 ± 1.0 8.8 (mV) Data Table