Article: Modulation of action potential firing by iberiotoxin and NS1619 in rat dorsal root ganglion neurons.
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Zhang XF; Gopalakrishnan M; Shieh CC
Neuroscience, 2003
Table 1Characteristics of electrical and pharmacological properties of small and medium size DRG neurons
| Small | Medium |
| Diameter (μm) | 23.5±0.4 (18–25)a | 37.6±0.9 (25–45)a |
| Number of neurons (n) | 30 | 22 |
| RMP (mV) | −57.4±0.7 | −55.3±2.8 |
| AP threshold (mV) | −20.4±1.0 | −23.3±1.1* |
| AP amplitude (mV) | 70.5±2.0 | 74.5±2.8 |
| AP duration (ms) | 6.7±0.5 | 4.3±0.5* |
| AHP (mV) | 40.6±1.4 | 34.6±1.6 |
| Threshold currents to evoke AP (nA) | 0.29±0.03 | 0.41±0.05 |
| Capsaicin-sensitive neurons (%) | 72 (18/25 cells) | 45 (9/20 cells) |
| IbTx-sensitive neurons (%) | 67 (6/9 cells) | 67 (6/9 cells) |
AP, action potential; RMP, resting membrane potential.aRange of approximate diameter of neuron.*Indicates significant difference, P<0.05, Students' t-test.
Inferred neuron-electrophysiology data values
