Article: Modulation of action potential firing by iberiotoxin and NS1619 in rat dorsal root ganglion neurons.
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Zhang XF; Gopalakrishnan M; Shieh CC
Neuroscience, 2003
Table 3Effects of NS1619 on passive electrical properties and action potentials in small and medium size neuronsa
| RMP3 (mV) | Threshold (mV) | Duration (ms) | Amplitude (mV) | AHP (mV) |
Small diameter neurons | | | |
Control | −57.3±0.8 (23) | −20.8±1.2 (23) | 6.3±0.5 (23) | 70.0±2.3 (23) | 40.7±1.5 (23) |
NS1619 | −57.1±0.8 (23) | −18.8±1.2** (23) | 9.0±0.7** (23) | 66.6±2.8** (23) | 42.8±1.4* (23) |
Medium diameter neurons | | | |
Control | −55.1±1.1 (9) | −23.1±1.2 (9) | 4.0±0.5 (9) | 77.3±4.1 (9) | 39.7±1.8 (9) |
NS1619 | −54.9±1.2 (9) | −20.6±1.7* (9) | 6.9±1.2** (9) | 71.0±3.8* (9) | 39.0±2.1 (9) |
aNumber of neurons tested is indicated in parenthese.*Indicates significant difference, P<0.05, Students' t-test, and**indicates significant difference; P<0.01, Students' t-test.
Inferred neuron-electrophysiology data values
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