Article: Neurochemical features and synaptic connections of large physiologically-identified GABAergic cells in the rat frontal cortex.
Full Text (publisher's website) ; Article Metadata ; Article Data (extracted) Kawaguchi Y; Kubota Y Neuroscience, 1998
Table 1Properties of cholecystokinin, somatostatin- and parvalbumin-immunoreactive non-pyramidal cells in the rat frontal cortex
Layer II/III non-pyramidal cells larger than 180μm2 in somatic area or than 18μm in longest extent of soma were included.Data are mean±S.D. values. n, number of cells. Ranges are given in parentheses.The temperature for recording was 30°C.*RS, regular-spiking; BS, burst-spiking; FS, fast-spiking.†Input resistance was determined with hyperpolarizing current pulses inducing a voltage shift of 6–15mV negative to rest. ‡At half amplitude. §Cross-sectional somatic areas and the longest extent of somata were measured from the 200μm sections containing whole stained cells.SOM(−), somatostatin-negative; CCK(−), CCK-negative.>A, <B, significantly larger than that of A cells and smaller than that of B cells, respectively (P≤0.01).CCK-RS, CCK RSNP cells; SOM-RS, somatostatin RSNP cells; PV-FS, parvalbumin FS cells.
Cholecystokinin (CCK) cells | Somatostatin (SOM) cells | Parvalbumin (PV) cells | ||
(n=17) | (n=18) | (n=12) | ||
Single immunofluorescence | n=10 | n=7 | n=9 | |
Double immunofluorescence | SOM(−), n=7 | CCK(−), n=11 | CCK(−), n=2 | |
SOM(−), n=1 | ||||
Firing type* | RS | BS | RS | FS |
(n=15) | (n=2) | (n=18) | (n=12) | |
Resting potential (mV) | −63±4 | −61 | −55±6 | −71±4 |
(−71, −57) | (−65, −57) | (−65, −46) | (−78, −66) | |
<SOM-RS, >PV-FS | >CCK-RS, >PV-FS | <CCK-RS, <SOM-RS | ||
Input resistance (MΩ)† | 380±118 | 372 | 353±212 | 168±61 |
(237–615) | (360, 383) | (204–1 121) | (86–314) | |
>PV-FS | >PV-FS | <CCK-RS, <SOM-RS | ||
Spike width (ms)‡ | 0.62±0.1 | 0.73 | 0.84±0.21 | 0.41±0.06 |
(0.52–0.8) | (0.7, 0.75) | (0.61–1.2) | (0.3–0.53) | |
<SOM-RS, >PV-FS | >CCK-RS, >PV-FS | <CCK-RS, <SOM-RS | ||
Somatic area (μm2)§ | 234±50 | 265 | 223±50 | 202±27 |
(176–351) | (256, 274) | (173–387) | (172–247) | |
Longest extent of soma (μm)§ | 22.9±3.2 | 26.8 | 22.4±3.5 | 19.8±3.0 |
(17.4–30.6) | (23.9, 29.6) | (16.9–29.4) | (15.5–25.4) |
Inferred neuron-electrophysiology data values
Neuron Type | Neuron Description | Ephys Prop | Extracted Value | Standardized Value | Content Source |
---|---|---|---|---|---|
Other | frontal cortex Layer 2/3 non-pyramidal cholecystokinin regular spiking neuron | resting membrane potential (mV) | -63.0 ± 4.0 (15) | -63.0 (mV) | Data Table |
Other | frontal cortex Layer 2/3 non-pyramidal cholecystokinin Gabaergic Burst Spiking Neuron | resting membrane potential (mV) | -61.0 (2) | -61.0 (mV) | Data Table |
Neocortex Martinotti cell | frontal cortex Layer 2/3 non-pyramidal Somatostatin expressing, Gabaergic Regular Spiking Neuron | resting membrane potential (mV) | -55.0 ± 6.0 (18) | -55.0 (mV) | Data Table |
Neocortex basket cell | Frontal Cortex Non-Pyramidal Parvalbumin expressing, Gabaergic Fast Spiking Neuron | resting membrane potential (mV) | -71.0 ± 4.0 (12) | -71.0 (mV) | Data Table |
Other | frontal cortex Layer 2/3 non-pyramidal cholecystokinin regular spiking neuron | input resistance (MΩ) | 380.0 ± 118.0 (15) | 380.0 (MΩ) | Data Table |
Other | frontal cortex Layer 2/3 non-pyramidal cholecystokinin Gabaergic Burst Spiking Neuron | input resistance (MΩ) | 372.0 (2) | 372.0 (MΩ) | Data Table |
Neocortex Martinotti cell | frontal cortex Layer 2/3 non-pyramidal Somatostatin expressing, Gabaergic Regular Spiking Neuron | input resistance (MΩ) | 353.0 ± 212.0 (18) | 353.0 (MΩ) | Data Table |
Neocortex basket cell | Frontal Cortex Non-Pyramidal Parvalbumin expressing, Gabaergic Fast Spiking Neuron | input resistance (MΩ) | 168.0 ± 61.0 (12) | 168.0 (MΩ) | Data Table |
Other | frontal cortex Layer 2/3 non-pyramidal cholecystokinin regular spiking neuron | spike half-width (ms) | 0.62 ± 0.1 (15) | 0.62 (ms) | Data Table |
Other | frontal cortex Layer 2/3 non-pyramidal cholecystokinin Gabaergic Burst Spiking Neuron | spike half-width (ms) | 0.73 (2) | 0.73 (ms) | Data Table |
Neocortex Martinotti cell | frontal cortex Layer 2/3 non-pyramidal Somatostatin expressing, Gabaergic Regular Spiking Neuron | spike half-width (ms) | 0.84 ± 0.21 (18) | 0.84 (ms) | Data Table |
Neocortex basket cell | Frontal Cortex Non-Pyramidal Parvalbumin expressing, Gabaergic Fast Spiking Neuron | spike half-width (ms) | 0.41 ± 0.06 (12) | 0.41 (ms) | Data Table |
Other | frontal cortex Layer 2/3 non-pyramidal cholecystokinin regular spiking neuron | cell diameter | 234.0 ± 50.0 (15) | 234.0 (um) | Data Table |
Other | frontal cortex Layer 2/3 non-pyramidal cholecystokinin Gabaergic Burst Spiking Neuron | cell diameter | 265.0 (2) | 265.0 (um) | Data Table |
Neocortex Martinotti cell | frontal cortex Layer 2/3 non-pyramidal Somatostatin expressing, Gabaergic Regular Spiking Neuron | cell diameter | 223.0 ± 50.0 (18) | 223.0 (um) | Data Table |
Neocortex basket cell | Frontal Cortex Non-Pyramidal Parvalbumin expressing, Gabaergic Fast Spiking Neuron | cell diameter | 202.0 ± 27.0 (12) | 202.0 (um) | Data Table |