Article: Survival of dentate hilar mossy cells after pilocarpine-induced seizures and their synchronized burst discharges with area CA3 pyramidal cells.
Table 2Characteristics of EPSPs evoked by outer molecular layer stimulation at threshold
Amplitude to peak (mV)
Latency to onset (ms)
Latency to peak (ms)
Half-duration (from onset) (ms)
Total duration (from onset) (ms)
Half-duration (from stimulus) (ms)
Total duration (from stimulus) (ms)
Interval onset to peak (ms)
Epileptic
Mean
13.0
10.4
24.7
57.6a
100.3
68.0a
108.3
14.3
S.E.M.
2.4
1.6
14.6
11.0
14.6
10.4
16.2
3.7
n
6
7
7
7
7
7
7
7
Status control
Mean
12.9
7.1
19.0
32.3
110.0b
39.0
103.5b
32.3
S.E.M.
2.4
1.6
4.3
4.7
–
6.6
–
4.7
n
4
4
3
3
1
3
1
3
Saline control
Mean
8.4
10.6
16.4
24.4a
67.0
33.9a
76.0
7.0
S.E.M.
2.4
2.6
2.3
2.9
15.2
2.6
15.3
1.3
n
6
6
6
6
6
6
6
6
Measurements of EPSPs evoked at threshold by outer molecular layer stimulation are shown for all experimental groups. Duration was measured from the onset of the EPSP (from onset) or the stimulus artifact (from stimulus). Some cells are not included because they were not tested at threshold, or the threshold response included no detectable PSP in response to stimuli that could evoke APs in subsequent trials (Fig. 8B).
aDifferences between the three groups were statistically significant by one-way ANOVA (P>0.05), and the epileptic vs. saline control means were significantly different by a Student’s t-test (P<0.05) conducted subsequently.bTotal duration was not measured in all cases because spontaneous activity often interrupted the late phase of EPSPs. Therefore, total durations of epileptic and saline control groups were compared statistically using Student’s t-tests. Differences were not significant (P>0.05).
