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Article: Hyperexcitability, interneurons, and loss of GABAergic synapses in entorhinal cortex in a model of temporal lobe epilepsy.

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Kumar SS; Buckmaster PS
J. Neurosci., 2006


Table 3.

Number of Nissl-stained and GAD65 mRNA-positive neurons per medial entorhinal cortex in control and epileptic rats

Control(n = 10) Epileptic(n = 8) p values(t test)
Nissl
    I–II
        Mean 107,900 72,500 <0.002
        SEM 7400 5200
        CV 0.217 0.201
        Mean CEa 0.087 0.101
    III
        Mean 110,100 53,300 <0.000001
        SEM 4400 4000
        CV 0.125 0.211
        Mean CE 0.058 0.089
    V–VI
        Mean 241,400 182,200 <0.009
        SEM 10,900 17,400
        CV 0.143 0.253
        mean CE 0.086 0.103
GAD
    I–VI
        Mean 38,500 28,700 <0.0003
        SEM 1400 1400
        CV 0.118 0.134
        Mean CE 0.050 0.062
  • CV, Coefficient of variation; CE, coefficient of error.

  • aMean CE was calculated as described by West et al. (1991).


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