Article: Functional role of the fast transient outward K+ current IA in pyramidal neurons in (rat) primary visual cortex.
Full Text (publisher's website) ; Article Metadata ; Article Data (extracted) Yuan W; Burkhalter A; Nerbonne JM J. Neurosci., 2005
Cm | Rin | RMP (mV) | APthresh (pA) | APA (mV) | APD50 (ms) | APD90 (ms) | AHP (mV) | |
---|---|---|---|---|---|---|---|---|
EGFP (n = 30) | 23 ± 2 | 1.1 ± 0.2 | −55 ± 1 | 40 ± 5 | 104 ± 3 | 3.8 ± 0.2 | 6.7 ± 0.4 | −7.8 ± 0.4 |
Kv4.2DN plus EGFP (n = 25) | 22 ± 2 | 1.6 ± 0.3* | −56 ± 4 | 20 ± 5** | 96 ± 6 | 8.4 ± 0.7** | 17.1 ± 1.3** | −1.9 ± 0.3** |
Kv2.1DN plus EGFP (n = 10) | 23 ± 2 | 1.2 ± 0.3 | −55 ± 2 | 39 ± 6 | 99 ± 6 | 3.8 ± 0.2 | 13.0 ± 0.7* | −3.4 ± 1.7* |
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RMP, Resting membrane potential; AHP, afterhyperpolarization; APthresh, current threshold to evolve a single action potential in response to a 5 ms depolarizing input; APA, action potential amplitude; ADP50 and ADP90, action potential durations at 50 and 90% repolarization.
aAll values are means ± SEM. Values are significantly different (*p < 0.05; **p < 0.01) from those determined in cells expressing EGFP alone.
Inferred neuron-electrophysiology data values
Neuron Type | Neuron Description | Ephys Prop | Extracted Value | Standardized Value | Content Source |
---|---|---|---|---|---|
Other | Primary visual cortex EGFP+ pyramidal neurons | cell capacitance | 23.0 ± 2.0 | 23.0 (pF) | Data Table |
Other | Primary visual cortex EGFP+ pyramidal neurons | input resistance | 1.1 ± 0.2 | -- | Data Table |
Other | Primary visual cortex EGFP+ pyramidal neurons | resting membrane potential (mV) | -55.0 ± 1.0 | -55.0 (mV) | Data Table |
Other | Primary visual cortex EGFP+ pyramidal neurons | spike threshold (pA) | 40.0 ± 5.0 | -- | Data Table |
Other | Primary visual cortex EGFP+ pyramidal neurons | spike amplitude (mV) | 104.0 ± 3.0 | 104.0 (mV) | Data Table |
Other | Primary visual cortex EGFP+ pyramidal neurons | spike half-width (ms) | 3.8 ± 0.2 | 3.8 (ms) | Data Table |
Other | Primary visual cortex EGFP+ pyramidal neurons | spike width (ms) | 6.7 ± 0.4 | 6.7 (ms) | Data Table |
Other | Primary visual cortex EGFP+ pyramidal neurons | AHP amplitude (mV) | -7.8 ± 0.4 | 7.8 (mV) | Data Table |