|
Article: Interleukin-1beta induces hyperpolarization and modulates synaptic inhibition in preoptic and anterior hypothalamic neurons.
Full Text (publisher's website) ; Article Metadata ; Article Data (extracted) Tabarean IV; Korn H; Bartfai T Neuroscience, 2006
Table 1Membrane properties of PO/AH neurons in control and after application of IL-1β (0.3 nM)
AHP, afterhyperpolarization; AP, action potential; Rinput, input resistance; s.p.f., spontaneous firing rate. All values are means±S.D.⁎P<0.05,⁎⁎P<0.01.
| Parameter | Control, mean±S.D. | Range | n | IL-1β, mean±S.D. | Range | n |
| r.m.p. (mV) | −57.7±4.9 | −49to−66 | 15 | −63.6±5.4⁎⁎ | −52to−71 | 15 |
| Rinput (MΩ) | 517±62 | 405to624 | 15 | 419±51⁎⁎ | 328to505 | 15 |
| S.p.f. (Hz) | 5.2±3.3 | 0to10.3 | 15 | 1.4±1.3⁎⁎ | 0to4.2 | 15 |
| AP amplitude (mV) | 69.7±4.4 | 61to76 | 15 | 70.6±4.3 | 61to77 | 12 |
| AP threshold (mV) | −42.1±3.6 | −36to−48 | 15 | −41.4±4.6 | −34to−50 | 12 |
| AP halfwidth (mV) | 0.88±0.05 | 0.79to0.96 | 15 | 0.97±0.07⁎ | 0.89to1.12 | 12 |
| AHP amplitude (mV) | −10.2±3.6 | −4to−15 | 15 | −8.9±2.8 | −4to−13 | 12 |
Inferred neuron-electrophysiology data values
| Neuron Type | Neuron Description | Ephys Prop | Extracted Value | Standardized Value | Content Source |
|---|---|---|---|---|---|
| Other | Preoptic anterior hypothalamus GABAergic neuron | input resistance (MΩ) | 517.0 ± 62.0 (15) | 517.0 (MΩ) | Data Table |
| Other | Preoptic anterior hypothalamus GABAergic neuron | spontaneous firing rate (Hz) | 5.2 ± 3.3 (15) | 5.2 (Hz) | Data Table |
| Other | Preoptic anterior hypothalamus GABAergic neuron | spike amplitude (mV) | 69.7 ± 4.4 (15) | 69.7 (mV) | Data Table |
| Other | Preoptic anterior hypothalamus GABAergic neuron | spike threshold (mV) | -42.1 ± 3.6 (15) | -42.1 (mV) | Data Table |
| Other | Preoptic anterior hypothalamus GABAergic neuron | spike half-width (mV) | 0.88 ± 0.05 (15) | -- | Data Table |
| Other | Preoptic anterior hypothalamus GABAergic neuron | AHP amplitude (mV) | -10.2 ± 3.6 (15) | 10.2 (mV) | Data Table |
| Other | Preoptic anterior hypothalamus GABAergic neuron | resting membrane potential (mV) | -57.7 ± 4.9 (15) | -57.7 (mV) | Data Table |