Article: Spike sequences and mean firing rate in rat neocortical neurons in vitro.
Full Text (publisher's website) ; Article Metadata ; Article Data (extracted) Karpuk N; Vorobyov V Brain Res., 2003
Table 1Electrophysiological parameters of rat neocortical neurons in vitro
DP(−), cells lacking afterdepolarizing potential (ADP); DP(+), cells showing ADP; AHP, afterhyperpolarizing potential; *P<0.05; **P<0.001; n.s., non-significant.
Neuronal | DP(−) (n=47) | DP(+) (n=42) | P | ||
parameters | Mean | S.E.M. | Mean | S.E.M. | |
Resting membrane potential, mV | −78.4 | 0.52 | −73.5 | 0.39 | * |
Membrane resistance, MΩ | 53.5 | 1.25 | 44.3 | 0.92 | * |
Time constant, ms | 9.0 | 0.24 | 7.3 | 0.24 | * |
Spike width, ms | 1.1 | 0.04 | 0.8 | 0.02 | * |
Spike threshold, mV | 41.5 | 1.70 | 30.9 | 1.60 | * |
Amplitude of action potential, mV | 102.7 | 1.70 | 97.5 | 1.80 | n.s. |
Max rate of spike rise, mV/ms | 175.4 | 5.60 | 217.4 | 7.50 | ** |
Max rate of spike fall, mV/ms | 56.3 | 2.05 | 87.5 | 3.04 | ** |
Amplitude of AHP, mV | −14.1 | 0.20 | −11.3 | 0.20 | ** |
Duration of AHP, ms | 21.2 | 0.67 | 31.5 | 0.98 | ** |