Article: Differential modulatory effects of norepinephrine on synaptically driven responses of layer V barrel field cortical neurons.
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Waterhouse BD; Mouradian R; Sessler FM; Lin RC
Brain Res., 2000
Table 2Effects of adrenergic agonists on the probability of synaptically evoked spiking in different classes of layer V cortical neurons
Probability of | Cell type |
evoked spikinga | Regular | Mixed | Intrinsic |
spiking | burst/spike | burst |
Norepinephrine (NE) | Increased | 6 | 7 | 1 |
n=21 | No change | 0 | 0 | 0 |
Decreased | 0 | 3 | 4 |
Phenylephrine (PE) | Increased | 2 | 3 | – |
n=8 | No change | 0 | 0 | – |
Decreased | 0 | 3b | – |
Combined results | Increased | 8 | 10 | 1 |
NE+PE | (100%) | (63%) | (20%) |
n=29 | No change | 0 | 0 | 0 |
(0%) | (0%) | (0%) |
Decreased | 0 | 6 | 4 |
(0%) | (37%) | (80%) |
aIncreased >20%, no change ≤20%, decreased >20%. bPE concentration ≥100 μM.
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