Article: Fos regulates neuronal activity in the nucleus accumbens.
Table 1Comparison of membrane properties of NAc neurons in wild-type and Fos mutant mice.
The passive and active membrane properties of medium spiny NAc neurons were measured by current clamp recordings from brain slices of wild-type and f/fc-fos-D1-cre mice. Values represent the mean±SEM for the number of neurons indicated (*p<0.05; Student's t-test). RMP: resting membrane potential; AP: action potential; AHP: after-hyperpolarization.
|Number of neurons||10||12|
|Passive membrane properties|
|Active membrane properties|
|Current to generate AP (nA)||0.29±0.04||0.20±0.01*|
|AP threshold (mV)||−33.93±1.09||−34.27±1.19|
|AP amplitude (mV)||74.86±1.86||67.83±1.67*|
|1/2 AP duration (ms)||1.09±0.05||1.17±0.04|
|AHP amplitude (mV)||13.51±1.05||9.83±0.67*|