AboutNeuron TypesElectrophysiology PropertiesArticlesFAQsData/APIGet Involved

Article: Elevated postsynaptic [Ca2+]i and L-type calcium channel activity in aged hippocampal neurons: relationship to impaired synaptic plasticity.

Full Text (publisher's website) ; Article Metadata ; Article Data (extracted)
Thibault O; Hadley R; Landfield PW
J. Neurosci., 2001


Table 1.

Basic neuronal parameters in young-adult and aged CA1 neurons

Young-adult (n = 15) Aged (n = 16)
Input resistance (MΩ) 58.9  ± 3.7 61.9  ± 3.3
Resting membrane potential (mV) −58.7  ± 1.1 −58.8  ± 1.3
Action potential threshold (μA) 151  ± 15 181  ± 15
Action potential amplitude (mV) 83.8  ± 1.3 81.9  ± 2.3
Action potential width at base (msec) 2.3  ± 0.2 2.4  ± 0.1
Action potentials during 20 sec train (n) 134.6  ± 8.4 126.9  ± 8.1
Action potentials during FFearly (n) 14  ± 0 14  ± 0
Action potentials during FFlate(n) 11.2  ± 1.3 10.2  ± 1.3
Interval, slicing to imaging (hr) 3.85  ± 0.4 4.3  ± 0.3
  • All values are mean ± SEM. No significant age-dependent differences were detected. Threshold was the synaptic stimulation electrode current necessary to trigger a Na+ action potential. Action potential amplitude was measured from the peak of the EPSP. Action potential number values (n) were obtained during the 7 Hz suprathreshold train of synaptic activation.


Report miscurated data

Inferred neuron-electrophysiology data values

Neuron Type Neuron Description Ephys Prop Extracted Value Standardized Value Content Source
Hippocampus CA1 pyramidal cell spike amplitude (mV) 83.8 ± 1.3 (15) 83.8 (mV) Data Table
Hippocampus CA1 pyramidal cell spike amplitude (mV) 81.9 ± 2.3 (16) 81.9 (mV) Data Table
Hippocampus CA1 pyramidal cell spike width (msec) 2.3 ± 0.2 (15) 2.3 (ms) Data Table
Hippocampus CA1 pyramidal cell spike width (msec) 2.4 ± 0.1 (16) 2.4 (ms) Data Table
Hippocampus CA1 pyramidal cell input resistance (MΩ) 58.9 ± 3.7 (15) 58.9 (MΩ) Data Table
Hippocampus CA1 pyramidal cell input resistance (MΩ) 61.9 ± 3.3 (16) 61.9 (MΩ) Data Table
Hippocampus CA1 pyramidal cell resting membrane potential (mV) -58.7 ± 1.1 (15) -58.7 (mV) Data Table
Hippocampus CA1 pyramidal cell resting membrane potential (mV) -58.8 ± 1.3 (16) -58.8 (mV) Data Table
Hippocampus CA1 pyramidal cell rheobase (μA) 151.0 ± 15.0 (15) -- Data Table
Hippocampus CA1 pyramidal cell rheobase (μA) 181.0 ± 15.0 (16) -- Data Table