Article: Blockade of neuronal activity during hippocampal development produces a chronic focal epilepsy in the rat.
Full Text (publisher's website) ; Article Metadata ; Article Data (extracted) Galvan CD; Hrachovy RA; Smith KL; Swann JW J. Neurosci., 2000
Table 1.
Summary of experiments
Experiment | Control number of rats | Experimental number of rats | Age when infusion began1-a | Duration of infusion (days) | Age when infusion stopped1-a | Age when results were obtained1-a |
---|---|---|---|---|---|---|
2-Deoxyglucose studies | 5 | 5 | 12 | 14 | 26 | 26 |
Cresyl violet studies | 5 | 5 | 12 | 28 | 40 | 40 |
In vivo EEG studies | ||||||
Recovery of neuronal activity after activity blockade | 6 | 15 | 12–17 | 28 | 40–45 | 40–54 |
Age dependence of effects of ac | 6 | 11 | 10–12 | 28 | 38–40 | 38–52 |
tivity blockade1-b | 6 | 10 | 13–17 | 28 | 41–45 | 41–57 |
2 | 6 | 45–50 | 28 | 73–78 | 73–90 | |
Follow-up at 6–8 months of age | 2 | 7 | 10–12 | 28 | 38–40 | 6–8 months |
Interictal spikes in dorsal vs ventral hippocampus | 5 | 5 | 10–12 | 28 | 38–40 | 26–40 |
Long-term video monitorings | 2 | 7 | 10–12 | 28 | 38–40 | 6–12 months |
In vitro slice studies | ||||||
Recordings of remote focus in vitro | 3 | 5 | 10–12 | 14–21 | 24–33 | 24–33 |
Recordings of epileptiform bursts 2 weeks after TTX withdrawal | 2 | 3 | 10–12 | 28 | 38–40 | 52–54 |
Blockade of minibursts by: | ||||||
KYN | 3 | 10–12 | 14–21 | 24–33 | 24–33 | |
CNQX | 3 | 10–12 | 14–21 | 24–33 | 24–33 | |
Whole-cell recordings | 3 | 7 | 10–12 | 14–24 | 24–33 | 24–33 |
Inferred neuron-electrophysiology data values
Neuron Type | Neuron Description | Ephys Prop | Extracted Value | Standardized Value | Content Source |
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