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Article: Blockade of neuronal activity during hippocampal development produces a chronic focal epilepsy in the rat.

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Galvan CD; Hrachovy RA; Smith KL; Swann JW
J. Neurosci., 2000


Table 2.

Comparison of the neurophysiological properties of CA3 pyramidal cells in experimental and control rats

Control Experimental
n 4 5 
Vm, mV −65  ± 4.2 −66  ± 3.6
Rm, MΩ 180  ± 21 161  ± 14.6
Spike amp, mV 73.9  ± 2.7 80.4  ± 3.2
Spike duration, ½ amplitude, msec 1.3  ± .01 1.1  ± .03
Intrinsic burst duration, msec 60.3  ± 1.4 63.2  ± 3.1
Number of spikes per burst 2.5  ± 0.5 2.3  ± 0.3
  • n = number of cells. Data are presented as mean ± SEM. Differences between all measures made in saline-infused (control) and TTX-infused (experimental) rats were not significant (p > 0.05).


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Inferred neuron-electrophysiology data values

Neuron Type Neuron Description Ephys Prop Extracted Value Standardized Value Content Source
Hippocampus CA3 pyramidal cell resting membrane potential (mV) -65.0 ± 4.2 (4) -65.0 (mV) Data Table
Hippocampus CA3 pyramidal cell input resistance (MΩ) 180.0 ± 21.0 (4) 180.0 (MΩ) Data Table
Hippocampus CA3 pyramidal cell spike amplitude (mV) 73.9 ± 2.7 (4) 73.9 (mV) Data Table
Hippocampus CA3 pyramidal cell spike half-width 1.3 ± 0.01 (4) 1.3 (ms) Data Table