TABLE 2.Purinergic agonist-produced current densities for LS and TL bladder sensory neurons from CYP-treated and control rats
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| Property | Treatment | LS Neurons | TL Neurons | |||
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| A. ATP | ||||||
| Percentage responding | Control | 96% (53/55) | 62% (33/53)* | |||
| CYP | 97% (59/61) | 85% (47/55)† | ||||
| Current density, pA/pF | ||||||
| Fast current | Control | 5.3 ± 0.6 | 4.4 ± 0.8 | |||
| CYP | n/a | 9.9 ± 1.2† | ||||
| Slow current | Control | 67.8 ± 11.0 | 4.7 ± 0.7* | |||
| CYP | 116.2 ± 12.0† | 8.7 ± 1.0† | ||||
| Mixed current | Control | 6.4 ± 0.4 | 5.6 ± 0.9 | |||
| CYP | n/a | 10.4 ± 0.8† | ||||
| B. αβ-metATP | ||||||
| Percentage responding | Control | 95% (52/55) | 51% (27/53)* | |||
| CYP | 92% (56/61) | 80% (44/55)† | ||||
| Current density, pA/pF | ||||||
| Fast current | Control | 2.1 ± 0.5 | 1.5 ± 0.3 | |||
| CYP | n/a | 4.4 ± 0.4† | ||||
| Slow current | Control | 28.4 ± 4.0 | 2.4 ± 0.7* | |||
| CYP | 51.5 ± 5.0† | 6.8 ± 0.2† | ||||
| Mixed current | Control | 2.7 ± 0.6 | 1.9 ± 0.3 | |||
| CYP | n/a | 5.1 ± 0.7† | ||||
Values are means ± SE, or percentages.
* P < 0.05 between LS and TL neuron groups;
† P < 0.05 between control and CYP treatment. n/a, not applicable.