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Article: Whole-cell plasticity in cocaine withdrawal: reduced sodium currents in nucleus accumbens neurons.

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Zhang XF; Hu XT; White FJ
J. Neurosci., 1998


Table 2.

Repeated cocaine administration did not alter whole-cell Na+ current in freshly dissociated cortical neurons

Control (n = 9) Cocaine (n = 8)
Na+ current density (nA/pF) 0.35  ± 0.03 0.34  ± 0.03
Half-maximal activation (mV) −34.8  ± 1.0 −36.9  ± 1.0
Activation slope (mV) 5.2  ± 0.6 4.9  ± 0.7
Half-maximal inactivation (mV) −61.8  ± 1.7 −62.8  ± 2.4
Inactivation slope (mV) 6.5  ± 0.5 6.4  ± 0.6

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Neuron Type Neuron Description Ephys Prop Extracted Value Standardized Value Content Source