SP+/nNOS+ (n = 18) | SP+/nNOS- (n = 5) | SP-/nNOS- (n = 24) | |
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Resting membrane potential (mV) | -55.3 ± 1.2**a, b | -68.0 ± 4.7 | -63.7 ± 1.4 |
Input resistance (MΩ) | 584 ± 46 | 335 ± 95 | 519 ± 91 |
Membrane time constant (ms) | 50.9 ± 5.5**b | 30.8 ± 9.9 | 28.7 ± 3.8 |
Action potential threshold (mV) | -45.3 ± 0.7 | -50.6 ± 1.3 | -45.4 ± 1.1 |
Action potential amplitude (mV) | 77.4 ± 2.3 | 75.5 ± 1.7 | 72.4 ± 1.7 |
Action potential duration (ms) | 1.24 ± 0.06*a | 0.85 ± 0.12 | 1.09 ± 0.07 |
AHP first component amplitude (mV) | -15.4 ± 0.7*b | -21.4 ± 1.3 | -19.8 ± 1.3 |
AHP first component latency (ms) | 5.7 ± 1.3 | 6.5 ± 2.7 | 8.3 ± 1.3 |
AHP second component amplitude (mV) | -16.3 ± 1.0 (n = 13) | -18.8 (n = 1) | -15.8 ± 2.1 (n = 7) |
AHP second component latency (ms) | 27.4 ± 4.1 (n = 13) | 15.4 (n = 1) | 21.1 ± 2.5 (n = 7) |
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Note: Statistical significance was assessed by Tukey-Kramer test.
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aComparison to SP+/nNOS-.
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bComparison to SP-/nNOS-.
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*P < 0.05; **P < 0.01.