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Article: Serotonin induces EPSCs preferentially in layer V pyramidal neurons of the frontal cortex in the rat.

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Lambe EK; Goldman-Rakic PS; Aghajanian GK
Cereb. Cortex, 2000


Table 1

Electrophysiological characteristics

Layer No. of cells Resting potential (mV) Spike height (mV) Spike width (ms) Input resistance (MΩ)
There were no significant differences across the layers in mean membrane and spike properties recorded in current clamp mode (mean ± SEM).
II/III 8 -76.3 ± 2.8 78.3 ± 2.2 0.6 ± 0.1 38.5 ± 2.1
V 8 -72.0 ± 1.5 73.4 ± 2.6 0.6 ± 0.1 41.1 ± 5.3
VI 8 -73.8 ± 2.9 70.0 ± 2.5 0.8 ± 0.1 43.4 ± 3.9

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Inferred neuron-electrophysiology data values

Neuron Type Neuron Description Ephys Prop Extracted Value Standardized Value Content Source
Neocortex pyramidal cell layer 5-6 Neocortex pyramidal cell layer 5 resting membrane potential (mV) -72.0 ± 1.5 (8) -72.0 (mV) Data Table
Neocortex pyramidal cell layer 5-6 Neocortex pyramidal cell layer 5 spike amplitude (mV) 73.4 ± 2.6 (8) 73.4 (mV) Data Table
Neocortex pyramidal cell layer 5-6 Neocortex pyramidal cell layer 5 spike half-width (ms) 0.6 ± 0.1 (8) 0.6 (ms) Data Table
Neocortex pyramidal cell layer 5-6 Neocortex pyramidal cell layer 5 input resistance (MΩ) 41.1 ± 5.3 (8) 41.1 (MΩ) Data Table
Neocortex pyramidal cell layer 5-6 Neocortex pyramidal cell layer 6 resting membrane potential (mV) -73.8 ± 2.9 (8) -73.8 (mV) Data Table
Neocortex pyramidal cell layer 5-6 Neocortex pyramidal cell layer 6 spike amplitude (mV) 70.0 ± 2.5 (8) 70.0 (mV) Data Table
Neocortex pyramidal cell layer 5-6 Neocortex pyramidal cell layer 6 spike half-width (ms) 0.8 ± 0.1 (8) 0.8 (ms) Data Table
Neocortex pyramidal cell layer 5-6 Neocortex pyramidal cell layer 6 input resistance (MΩ) 43.4 ± 3.9 (8) 43.4 (MΩ) Data Table
Neocortex pyramidal cell layer 2-3 resting membrane potential (mV) -76.3 ± 2.8 (8) -76.3 (mV) Data Table
Neocortex pyramidal cell layer 2-3 spike amplitude (mV) 78.3 ± 2.2 (8) 78.3 (mV) Data Table
Neocortex pyramidal cell layer 2-3 spike half-width (ms) 0.6 ± 0.1 (8) 0.6 (ms) Data Table
Neocortex pyramidal cell layer 2-3 input resistance (MΩ) 38.5 ± 2.1 (8) 38.5 (MΩ) Data Table