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Article: A selective interplay between aberrant EPSPKA and INaP reduces spike timing precision in dentate granule cells of epileptic rats.

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Epsztein J; Sola E; Represa A; Ben-Ari Y; Crépel V
Cereb. Cortex, 2010


Table 1

Intrinsic properties of DGCs from control and epileptic rats

Control Epileptic
Resting membrane potential (mV) -70.5 ± 0.7 (n = 32) -68.3 ± 0.3 (n = 28)
Input resistance (MΩ) 260.2 ± 22.0 (n = 32) 221.0 ± 13.3 (n = 28)
Membrane time constant (ms) 17.7 ± 1.6 (n = 32) 19.9 ± 1.3 (n = 28)
Action potential firing threshold (mV) -40.6 ± 1.2 (n = 20) -40.7 ± 1.1 (n = 23)
Spike amplitude (mV) 53.7 ± 5.7 (n = 20) 54.1 ± 6.0 (n = 23)
Spike half width (ms) 1.05 ± 0.07 (n = 20) 0.91 ± 0.04 (n = 23)
Firing probability (%) 50.6 ± 6.4 (n = 20) 49.6 ± 3.9 (n = 23)

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Inferred neuron-electrophysiology data values

Neuron Type Neuron Description Ephys Prop Extracted Value Standardized Value Content Source
Dentate gyrus granule cell membrane time constant (ms) 17.7 ± 1.6 (32) 17.7 (ms) Data Table
Dentate gyrus granule cell spike threshold (mV) -40.6 ± 1.2 (32) -40.6 (mV) Data Table
Dentate gyrus granule cell spike amplitude (mV) 53.7 ± 5.7 (32) 53.7 (mV) Data Table
Dentate gyrus granule cell spike half-width (ms) 1.05 ± 0.07 (32) 1.05 (ms) Data Table
Dentate gyrus granule cell resting membrane potential (mV) -70.5 ± 0.7 (32) -70.5 (mV) Data Table
Dentate gyrus granule cell input resistance (MΩ) 260.2 ± 22.0 (32) 260.2 (MΩ) Data Table