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Article: The association between breast tissue optical content and mammographic density in pre- and post-menopausal women.

Full Text (publisher's website) ; Article Metadata ; Article Data (extracted)
Blackmore KM; Knight JA; Walter J; Lilge L
PLoS ONE, 2015


10.1371/journal.pone.0115851.t001 Constraints and penalties employed in fitting algorithm used to obtain chromophore concentrations and scattering parameters.
Optical Parameter Range of Values Type of Constraint
Total Hemoglobin Concentration (µM) ≥ 0 µM, ≤ 56 µM Rigid Constraint1
Hemoglobin Oxygen Saturation (StO2, %) ≥ 0%, ≤ 100% Rigid Constraint
Lipid Concentration (%) ≥ 0%, ≤ 100% Rigid Constraint
Water Concentration (%) ≥ 0%, ≤ 100% Rigid Constraint
Scatter Amplitude (cm-1) ≥ 1cm-1, ≤ 40cm-1 Rigid Constraint
Scatter Power ≥ 0.05, ≤ 5.0 Rigid Constraint
Sum of Chromophore Concentrations (%) ≥ 0%, ≤ 100% Penalty2
Amplitude of Best-Fit Spectrum > Amplitude of Participant Spectrum Penalty

1Rigid constraints are restrictions on the fit such that if the value being constrained is out of range, those fit parameters are rejected by the algorithm. The fit algorithm will go back to the previous set of fit parameters and will continue the search for a minimum in another direction

2Penalties are constraints where if the value being constrained is out of range, a fixed penalty value is added to the X2 value for each instance where the fit value is out of range to artificially indicate that the fit is not good


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Inferred neuron-electrophysiology data values

Neuron Type Neuron Description Ephys Prop Extracted Value Standardized Value Content Source