AboutNeuron TypesElectrophysiology PropertiesArticlesFAQsData/APIGet Involved

Article: Sympathetic sprouting near sensory neurons after nerve injury occurs preferentially on spontaneously active cells and is reduced by early nerve block.

Full Text (publisher's website) ; Article Metadata ; Article Data (extracted)
Xie W; Strong JA; Li H; Zhang JM
J. Neurophysiol., 2007



TABLE 2.Effect of K+ channel blockers on spontaneous activity


Axotomy + ACSF Axotomy + TEA Axotomy + 4-AP

Number of animals 3 3 3
Incidence of Spontaneous activity, % 21.1 ± 0.5 31.5 ± 1.0 31.8 ± 2.9
P value vs. ACSF 0.0001 0.0001
Total number of fibers recorded 503 555 576

Incidence of spontaneous activity determined on post-operative day (POD) 7 after perfusion of the injured nerve with K+ blockers TEA (10 mM) or 4-aminopyridine (4-AP; 10 mM), or with vehicle (ACSF). The pump was still in place at the time spontaneous activity was measured. SEs are based on comparison between different animals. P values are based on Fisher's exact tests on the combined data. There was no significant difference between the TEA and 4-AP groups.

Report miscurated data

Inferred neuron-electrophysiology data values

Neuron Type Neuron Description Ephys Prop Extracted Value Standardized Value Content Source