Article: Kv4.2 mediates histamine modulation of preoptic neuron activity and body temperature.
Full Text (publisher's website) ; Article Metadata ; Article Data (extracted) Sethi J; Sanchez-Alavez M; Tabarean IV PLoS ONE, 2011
Parameter | w-t |
|
Kv4.2-/- |
|
r.m.p. (mV) | -52.3±4.4 | 14 | -50.6±5.1* | 15 |
Rinput (MΩ) | 407±62 | 14 | 427±53 | 15 |
S. f. r. (Hz) | 10.2±3.7 | 14 | 9.4±3.5 | 15 |
AP amplitude (mV) | 77.2±4.4 | 14 | 78.3±5.7 | 15 |
AP threshold (mV) | -43±3 | 14 | -44±4 | 15 |
AP halfwidth (mV) | 0.8±0.1 | 14 | 0.9±0.1 | 15 |
AHP amplitude (mV) | -17.8±3.1 | 14 | -19.2±3.2 | 15 |
AHP time to peak (ms) | 5.5±3.4 | 14 | 4.9±3.9 | 15 |
AHP decay (mV/ms) | 0.23±0.22 | 14 | 0.25±0.2 | 15 |
Peak IA density at 0 mV (pA/pF) | 58.6±19.5 | 14 | 41.8±12.9* | 15 |
ISS density at 0 mV (pA/pF) | 45.4±19.5 | 14 | 82.3±27.5** | 15 |
Values are presented as mean ± S.D., * and ** indicate P<0.05 and P<0.01, respectively (unpaired t-tests), (n)-number of cells.
Inferred neuron-electrophysiology data values
Neuron Type | Neuron Description | Ephys Prop | Extracted Value | Standardized Value | Content Source |
---|---|---|---|---|---|
Other | Hypothalamus median preoptic nucleus GABAergic pacemaker-firing cell | input resistance (MΩ) | 407.0 ± 62.0 (14) | 407.0 (MΩ) | Data Table |
Other | Hypothalamus median preoptic nucleus GABAergic pacemaker-firing cell | spontaneous firing rate (Hz) | 10.2 ± 3.7 (14) | 10.2 (Hz) | Data Table |
Other | Hypothalamus median preoptic nucleus GABAergic pacemaker-firing cell | spike amplitude (mV) | 77.2 ± 4.4 (14) | 77.2 (mV) | Data Table |
Other | Hypothalamus median preoptic nucleus GABAergic pacemaker-firing cell | spike threshold (mV) | -43.0 ± 3.0 (14) | -43.0 (mV) | Data Table |
Other | Hypothalamus median preoptic nucleus GABAergic pacemaker-firing cell | spike half-width (mV) | 0.8 ± 0.1 (14) | -- | Data Table |
Other | Hypothalamus median preoptic nucleus GABAergic pacemaker-firing cell | AHP amplitude (mV) | -17.8 ± 3.1 (14) | 17.8 (mV) | Data Table |
Other | Hypothalamus median preoptic nucleus GABAergic pacemaker-firing cell | AHP duration (ms) | 5.5 ± 3.4 (14) | 5.5 (ms) | Data Table |
Other | Hypothalamus median preoptic nucleus GABAergic pacemaker-firing cell | resting membrane potential (mV) | -52.3 ± 4.4 (14) | -52.3 (mV) | Data Table |