Article: Focal cortical lesions induce bidirectional changes in the excitability of fast spiking and non fast spiking cortical interneurons.
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Imbrosci B; Neitz A; Mittmann T
PLoS ONE, 2014
10.1371/journal.pone.0111105.t001
Intrinsic membrane and synaptic properties of Fs and Non Fs interneurons in sham-operated and lesion-treated mice.
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|
Fs Sham |
Fs Lesion |
Non Fs Sham |
Non Fs Lesion |
| Spike half-width |
0.345±0.011 ms (10) |
0.344±0.015 ms (9) |
0.623±0.015 ms (52) |
0.639±0.021 ms (48) |
| Adapt. Coeff. |
0.774±0.019 |
0.798±0.042 |
0.451±0.013 |
0.477±0.017 |
| Input resistance |
117.7±12.12 MΩ |
109.88±15.35 MΩ |
160.98±11.65 MΩ |
152.44±10.27 MΩ |
| Max. firing rate |
315±23.59 Hz |
301±21.9 Hz |
102.08±8.8 Hz |
97.5±9.13 Hz |
| Resting Vm |
-67.20±1.99 mV |
-69.22±1.99 mV |
-70.13±0.98 mV |
-66.12±0.90 mV |
| sEPSC amplitude |
22.39±1.80 pA (10) |
17.34±1.12 pA (9) |
13.93±0.88 pA (33) |
13.36±0.54 pA (34) |
| sEPSC frequency |
18.07±2.18 Hz |
17.82±1.72 Hz |
5.07±0.44 Hz |
7.99±0.73 Hz |
| sEPSC rise time |
0.434±0.024 ms |
0.437±0.043 ms |
2.521±0.35 ms |
0.638±0.041 ms |
| sEPSC decay time |
2.889±0.134 ms |
2.521±0.35 ms |
3.802±0.263 ms |
4.153±0.337 ms |
| ECA/s |
6.61±1.09 nA/s |
5.02±0.61 nA/s |
5.96±0.64 nA/s |
9.05±0.96 nA/s |
| PPR (20 ms) |
- |
- |
1.49±0.14 (9) |
1.20±0.07 (13) |
| PPR (30 ms) |
- |
- |
1.32±0.06 (11) |
1.42±0.12 (14) |
| PPR (50 ms) |
- |
- |
1.28±0.12 (10) |
1.29±0.11 (14) |
The numbers in parenthesis indicate the number of recorded neurons.
Inferred neuron-electrophysiology data values
