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Article: Neurophysiological modification of CA1 pyramidal neurons in a transgenic mouse expressing a truncated form of disrupted-in-schizophrenia 1.

Full Text (publisher's website) ; Article Metadata ; Article Data (extracted)
Booth CA; Brown JT; Randall AD
Eur. J. Neurosci., 2014


Table 2. Details of AP properties (mean ± SEM) of CA1-PNs from 3- to 4-month-old DISC1tr and WT littermates
WT (n = 19)DISC1tr (n = 23) P
AP peak (mV)31.1 ± 1.331.7 ± 1.30.8
AP width at -15 mV (ms)0.86 ± 0.020.88 ± 0.020.5
AP threshold (mV)-57.1 ± 0.8-56.8 ± 1.00.8
AP max. RoR (mV/ms)443 ± 17452 ± 190.7

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Inferred neuron-electrophysiology data values

Neuron Type Neuron Description Ephys Prop Extracted Value Standardized Value Content Source
Hippocampus CA1 pyramidal cell spike threshold (mV) -57.1 ± 0.8 (19) -57.1 (mV) Data Table
Hippocampus CA1 pyramidal cell spike threshold (mV) -56.8 ± 1.0 (23) -56.8 (mV) Data Table
Hippocampus CA1 pyramidal cell spike max rise slope (mV/ms) 443.0 ± 17.0 (19) 443.0 (mV/ms) Data Table
Hippocampus CA1 pyramidal cell spike max rise slope (mV/ms) 452.0 ± 19.0 (23) 452.0 (mV/ms) Data Table
Hippocampus CA1 pyramidal cell spike peak (mV) 31.1 ± 1.3 (19) 31.1 (mV) Data Table
Hippocampus CA1 pyramidal cell spike peak (mV) 31.7 ± 1.3 (23) 31.7 (mV) Data Table
Hippocampus CA1 pyramidal cell spike width (ms) 0.86 ± 0.02 (19) 0.86 (ms) Data Table
Hippocampus CA1 pyramidal cell spike width (ms) 0.88 ± 0.02 (23) 0.88 (ms) Data Table