AboutNeuron TypesElectrophysiology PropertiesArticlesFAQsData/APIGet Involved

Article: Spatial profile of excitatory and inhibitory synaptic connectivity in mouse primary auditory cortex.

Full Text (publisher's website) ; Article Metadata ; Article Data (extracted)
Levy RB; Reyes AD
J. Neurosci., 2012


Table 1.

Intrinsic membrane properties by cell type

P, n = 49 WT FS, n = 52 G42, n = 26 WT non-FS, n = 57 GIN, n = 46 p (GIN versus WT non-FS)
Mean SD Mean SD Mean SD Mean SD Mean SD
Age, d 22.6 3.5 22.7 2.7 22.1 2.5 21.3 3.2 24.8 3.8 <0.001
Max. firing rate, Hz 44.7 18.9 201.7 44.7 229.1 50.7 89.3 48.4 96.9 51.8
Resting Vm, mV -66.5 5.6 -68.0 6.4 -67.8 6.1 -65.6 6.7 -61.9 6.8 0.01
Rin, MΩ 126.4 82.7 119.5 36.6 119.4 38.9 195.0 88.8 279.6 85.8 <0.001
taum, ms 18.4 4.2 8.6 3.3 8.1 1.9 15.7 6.7 16.5 5.2
ISI(last) / ISI(first) 3.64 1.48 1.27 0.39 1.29 0.35 3.24 1.65 4.83 2.90 0.01
AP width, ms 1.20 0.20 0.48 0.10 0.48 0.10 0.98 0.32 0.91 0.38
AHP time, ms 31.6 9.5 3.5 1.6 4.5 3.2 12.4 9.7 32.7 17.5 <0.001
AHP amplitude, mV -17.1 3.6 -16.5 3.4 -15.1 5.3 -13.5 3.9 -11.4 2.7 0.003
Vthresh, mV -41.5 3.5 -40.0 6.0 -38.2 6.1 -38.1 7.6 -40.6 5.9 0.04
Rheobase I, nA 0.09 0.04 0.20 0.08 0.20 0.10 0.13 0.00 0.06 0.05 0.01
  • Values are derived from responses to hyperpolarizing and depolarizing current steps (compare Fig. 1B). Max., maximum; Rin, input resistance; taum, membrane time constant; ISI(last)/ISI(first), degree of spike rate adaptation; Vthresh, spike threshold. Other terms as defined in main text.


Report miscurated data

Inferred neuron-electrophysiology data values

Neuron Type Neuron Description Ephys Prop Extracted Value Standardized Value Content Source
Neocortex interneuron deep primary auditory cortex layer 2-4 fast-spiking inhibitory cell AHP amplitude (mV) -16.5 (52) 16.5 (mV) Data Table
Neocortex basket cell primary auditory cortex layer 2-4 fast-spiking parvalbumin-positive GFP-expressing round basket cell AHP amplitude (mV) -15.1 (26) 15.1 (mV) Data Table
Neocortex Martinotti cell primary auditory cortex layer 2-4 non-fast-spiking inhibitory cell AHP amplitude (mV) -13.5 (57) 13.5 (mV) Data Table
Neocortex Martinotti cell primary auditory cortex layer 2-4 non-fast-spiking somatostatin-positive GFP-expressing Martinotti cell AHP amplitude (mV) -11.4 (46) 11.4 (mV) Data Table
Neocortex pyramidal cell layer 2-3 primary auditory cortex layer 2-4 apical pyramidal cell spike threshold (mV) -41.5 (49) -41.5 (mV) Data Table
Neocortex interneuron deep primary auditory cortex layer 2-4 fast-spiking inhibitory cell spike threshold (mV) -40.0 (52) -40.0 (mV) Data Table
Neocortex basket cell primary auditory cortex layer 2-4 fast-spiking parvalbumin-positive GFP-expressing round basket cell spike threshold (mV) -38.2 (26) -38.2 (mV) Data Table
Neocortex Martinotti cell primary auditory cortex layer 2-4 non-fast-spiking inhibitory cell spike threshold (mV) -38.1 (57) -38.1 (mV) Data Table
Neocortex Martinotti cell primary auditory cortex layer 2-4 non-fast-spiking somatostatin-positive GFP-expressing Martinotti cell spike threshold (mV) -40.6 (46) -40.6 (mV) Data Table
Neocortex pyramidal cell layer 2-3 primary auditory cortex layer 2-4 apical pyramidal cell rheobase (nA) 0.09 (49) 90.0 (pA) Data Table
Neocortex interneuron deep primary auditory cortex layer 2-4 fast-spiking inhibitory cell rheobase (nA) 0.2 (52) 200.0 (pA) Data Table
Neocortex basket cell primary auditory cortex layer 2-4 fast-spiking parvalbumin-positive GFP-expressing round basket cell rheobase (nA) 0.2 (26) 200.0 (pA) Data Table
Neocortex Martinotti cell primary auditory cortex layer 2-4 non-fast-spiking inhibitory cell rheobase (nA) 0.13 (57) 130.0 (pA) Data Table
Neocortex Martinotti cell primary auditory cortex layer 2-4 non-fast-spiking somatostatin-positive GFP-expressing Martinotti cell rheobase (nA) 0.06 (46) 60.0 (pA) Data Table
Neocortex pyramidal cell layer 2-3 primary auditory cortex layer 2-4 apical pyramidal cell maximum firing rate (Hz) 44.7 (49) 44.7 (Hz) Data Table
Neocortex interneuron deep primary auditory cortex layer 2-4 fast-spiking inhibitory cell maximum firing rate (Hz) 201.7 (52) 201.7 (Hz) Data Table
Neocortex basket cell primary auditory cortex layer 2-4 fast-spiking parvalbumin-positive GFP-expressing round basket cell maximum firing rate (Hz) 229.1 (26) 229.1 (Hz) Data Table
Neocortex Martinotti cell primary auditory cortex layer 2-4 non-fast-spiking inhibitory cell maximum firing rate (Hz) 89.3 (57) 89.3 (Hz) Data Table
Neocortex Martinotti cell primary auditory cortex layer 2-4 non-fast-spiking somatostatin-positive GFP-expressing Martinotti cell maximum firing rate (Hz) 96.9 (46) 96.9 (Hz) Data Table
Neocortex pyramidal cell layer 2-3 primary auditory cortex layer 2-4 apical pyramidal cell resting membrane potential (mV) -66.5 (49) -66.5 (mV) Data Table
Neocortex interneuron deep primary auditory cortex layer 2-4 fast-spiking inhibitory cell resting membrane potential (mV) -68.0 (52) -68.0 (mV) Data Table
Neocortex basket cell primary auditory cortex layer 2-4 fast-spiking parvalbumin-positive GFP-expressing round basket cell resting membrane potential (mV) -67.8 (26) -67.8 (mV) Data Table
Neocortex Martinotti cell primary auditory cortex layer 2-4 non-fast-spiking inhibitory cell resting membrane potential (mV) -65.6 (57) -65.6 (mV) Data Table
Neocortex Martinotti cell primary auditory cortex layer 2-4 non-fast-spiking somatostatin-positive GFP-expressing Martinotti cell resting membrane potential (mV) -61.9 (46) -61.9 (mV) Data Table
Neocortex pyramidal cell layer 2-3 primary auditory cortex layer 2-4 apical pyramidal cell input resistance (MΩ) 126.4 (49) 126.4 (MΩ) Data Table
Neocortex interneuron deep primary auditory cortex layer 2-4 fast-spiking inhibitory cell input resistance (MΩ) 119.5 (52) 119.5 (MΩ) Data Table
Neocortex basket cell primary auditory cortex layer 2-4 fast-spiking parvalbumin-positive GFP-expressing round basket cell input resistance (MΩ) 119.4 (26) 119.4 (MΩ) Data Table
Neocortex Martinotti cell primary auditory cortex layer 2-4 non-fast-spiking inhibitory cell input resistance (MΩ) 195.0 (57) 195.0 (MΩ) Data Table
Neocortex Martinotti cell primary auditory cortex layer 2-4 non-fast-spiking somatostatin-positive GFP-expressing Martinotti cell input resistance (MΩ) 279.6 (46) 279.6 (MΩ) Data Table
Neocortex pyramidal cell layer 2-3 primary auditory cortex layer 2-4 apical pyramidal cell membrane time constant (ms) 18.4 (49) 18.4 (ms) Data Table
Neocortex interneuron deep primary auditory cortex layer 2-4 fast-spiking inhibitory cell membrane time constant (ms) 8.6 (52) 8.6 (ms) Data Table
Neocortex basket cell primary auditory cortex layer 2-4 fast-spiking parvalbumin-positive GFP-expressing round basket cell membrane time constant (ms) 8.1 (26) 8.1 (ms) Data Table
Neocortex Martinotti cell primary auditory cortex layer 2-4 non-fast-spiking inhibitory cell membrane time constant (ms) 15.7 (57) 15.7 (ms) Data Table
Neocortex Martinotti cell primary auditory cortex layer 2-4 non-fast-spiking somatostatin-positive GFP-expressing Martinotti cell membrane time constant (ms) 16.5 (46) 16.5 (ms) Data Table
Neocortex pyramidal cell layer 2-3 primary auditory cortex layer 2-4 apical pyramidal cell adaptation ratio (last/first ISI) 3.64 (49) 3.64 (ratio) Data Table
Neocortex interneuron deep primary auditory cortex layer 2-4 fast-spiking inhibitory cell adaptation ratio (last/first ISI) 1.27 (52) 1.27 (ratio) Data Table
Neocortex basket cell primary auditory cortex layer 2-4 fast-spiking parvalbumin-positive GFP-expressing round basket cell adaptation ratio (last/first ISI) 1.29 (26) 1.29 (ratio) Data Table
Neocortex Martinotti cell primary auditory cortex layer 2-4 non-fast-spiking inhibitory cell adaptation ratio (last/first ISI) 3.24 (57) 3.24 (ratio) Data Table
Neocortex Martinotti cell primary auditory cortex layer 2-4 non-fast-spiking somatostatin-positive GFP-expressing Martinotti cell adaptation ratio (last/first ISI) 4.83 (46) 4.83 (ratio) Data Table
Neocortex pyramidal cell layer 2-3 primary auditory cortex layer 2-4 apical pyramidal cell spike half-width (ms) 1.2 (49) 1.2 (ms) Data Table
Neocortex interneuron deep primary auditory cortex layer 2-4 fast-spiking inhibitory cell spike half-width (ms) 0.48 (52) 0.48 (ms) Data Table
Neocortex basket cell primary auditory cortex layer 2-4 fast-spiking parvalbumin-positive GFP-expressing round basket cell spike half-width (ms) 0.48 (26) 0.48 (ms) Data Table
Neocortex Martinotti cell primary auditory cortex layer 2-4 non-fast-spiking inhibitory cell spike half-width (ms) 0.98 (57) 0.98 (ms) Data Table
Neocortex Martinotti cell primary auditory cortex layer 2-4 non-fast-spiking somatostatin-positive GFP-expressing Martinotti cell spike half-width (ms) 0.91 (46) 0.91 (ms) Data Table
Neocortex pyramidal cell layer 2-3 primary auditory cortex layer 2-4 apical pyramidal cell AHP duration (ms) 31.6 (49) 31.6 (ms) Data Table
Neocortex interneuron deep primary auditory cortex layer 2-4 fast-spiking inhibitory cell AHP duration (ms) 3.5 (52) 3.5 (ms) Data Table
Neocortex basket cell primary auditory cortex layer 2-4 fast-spiking parvalbumin-positive GFP-expressing round basket cell AHP duration (ms) 4.5 (26) 4.5 (ms) Data Table
Neocortex Martinotti cell primary auditory cortex layer 2-4 non-fast-spiking inhibitory cell AHP duration (ms) 12.4 (57) 12.4 (ms) Data Table
Neocortex Martinotti cell primary auditory cortex layer 2-4 non-fast-spiking somatostatin-positive GFP-expressing Martinotti cell AHP duration (ms) 32.7 (46) 32.7 (ms) Data Table
Neocortex pyramidal cell layer 2-3 primary auditory cortex layer 2-4 apical pyramidal cell AHP amplitude (mV) -17.1 (49) 17.1 (mV) Data Table