Parameter | 5-HT neuron (n = 43) | 5-HT/GAD67 neuron (n = 10) | GAD67 neuron (n = 4) |
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Resting membrane potential (mV) | -61.82 ± 1.67 | -64.91 ± 4.14 | -52.13 ± 17.17 |
Threshold (mV) | -27.36 ± 1.05 | -31.06 ± 1.50 | -24.06 ± 7.04 |
Action potential amplitude (mV) | 70.37 ± 2.65 | 68.94 ± 3.94 | 45.30 ± 5.59* |
Action potential duration (ms) | 2.22 ± 0.12 | 1.98 ± 0.24 | 1.78 ± 0.22 |
Afterhyperpolarization (mV) | -25.66 ± 1.22 | -24.14 ± 1.31 | -29.00 ± 7.91 |
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Significantly lower amplitudes of action potentials are observed in GAD67 neurons among the three neuronal groups (F(2,54) = 4.372;
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↵*p < 0.05). No significant differences were found in the action potential duration [F(2,54) = 0.982, not significant (n.s.)], afterhyperpolarization (F(2,54) = 0.856, n.s.), or resting membrane potential (F(2,54) = 1.707, n.s.) among the three groups.