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Article: Aging-Related Hyperexcitability in CA3 Pyramidal Neurons Is Mediated by Enhanced A-Type K+ Channel Function and Expression.

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Simkin D; Hattori S; Ybarra N; Musial TF; Buss EW; Richter H; Oh MM; Nicholson DA; Disterhoft JF
J. Neurosci., 2015


Table 2.

Medium and slow AHP measures with and without GABA blockers

Group 15 AP current injection 5 orthodromic APs
Peak AHP 1 s Peak AHP 1 s
Young aCSF -8.01 ± 0.43 (52) -5.15 ± 0.35 -14.39 ± 1.08 (13) -7.22 ± 1.03
Aged aCSF -7.84 ± 0.42 (44) -4.87 ± 0.36 -15.49 ± 1.03 (18) -6.63 ± 0.53
Young aCSF-GABA -7.00 ± 0.83 (13) -4.56 ± 0.72 -7.35 ± 0.91 (13) -4.30 ± 0.78
Aged aCSF-GABA -7.78 ± 0.85 (13) -5.11 ± 0.67 -8.47 ± 0.64 (18) -4.91 ± 0.44

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Inferred neuron-electrophysiology data values

Neuron Type Neuron Description Ephys Prop Extracted Value Standardized Value Content Source