Article: Stimulation of D1-type dopamine receptors enhances excitability in prefrontal cortical pyramidal neurons in a state-dependent manner.
Full Text (publisher's website) ; Article Metadata ; Article Data (extracted) Lavin A; Grace AA Neuroscience, 2001
Control (n=10) | Dopamine | |
---|---|---|
Membrane potential (mV) | 74.2±8.3 | 66.4±9.7* |
Spike threshold (mV) | 48.6±7.0 | 49.5±7.1 |
Current threshold (pA) | 50±38 | 71±46 |
Spike amplitude (mV) | 56.4±5.6 | 63.4±8.7 |
Amplitude AHP (mV) | 12.0±8.4 | 3.6±1.9 |
Input resistance (MΩ) | 47.1±16.9 | 36.5±26.4 |
Excitability (slope #spikes/I) | 0.37±0.22 | 0.49±0.41 |
Inferred neuron-electrophysiology data values
Neuron Type | Neuron Description | Ephys Prop | Extracted Value | Standardized Value | Content Source |
---|---|---|---|---|---|
Neocortex pyramidal cell layer 5-6 | Prefrontal cortex layer 5-6 pyramidal neuron | spike amplitude (mV) | 56.4 ± 5.6 | 56.4 (mV) | Data Table |
Neocortex pyramidal cell layer 5-6 | Prefrontal cortex layer 5-6 pyramidal neuron | AHP amplitude (mV) | 12.0 ± 8.4 | 12.0 (mV) | Data Table |
Neocortex pyramidal cell layer 5-6 | Prefrontal cortex layer 5-6 pyramidal neuron | input resistance (MΩ) | 47.1 ± 16.9 | 47.1 (MΩ) | Data Table |
Neocortex pyramidal cell layer 5-6 | Prefrontal cortex layer 5-6 pyramidal neuron | resting membrane potential (mV) | 74.2 ± 8.3 | -74.2 (mV) | Data Table |
Neocortex pyramidal cell layer 5-6 | Prefrontal cortex layer 5-6 pyramidal neuron | spike threshold (mV) | 48.6 ± 7.0 | -48.6 (mV) | Data Table |
Neocortex pyramidal cell layer 5-6 | Prefrontal cortex layer 5-6 pyramidal neuron | rheobase (pA) | 50.0 ± 38.0 | 50.0 (pA) | Data Table |