Article: Electrophysiological properties of genetically identified subtypes of layer 5 neocortical pyramidal neurons: Ca²⁺ dependence and differential modulation by norepinephrine.
Full Text (publisher's website) ; Article Metadata ; Article Data (extracted) Guan D; Armstrong WE; Foehring RC J. Neurophysiol., 2015
Firing Rate, 2 s, Hz | f-I Slope, 200 ms, Hz/nA | f-I Slope, 2 s, Hz/nA | % Adaptation | Adaptation Index | |
---|---|---|---|---|---|
Etv1 | |||||
Control | 15 ± 3 (8) | 101 ± 9 (10) | 40 ± 12 (10) | 82 ± 3 (10) | 35 ± 11 (10) |
Apamin | 12 ± 2 (8) | 108 ± 14 (10) | 45 ± 13 (10) | 82 ± 5 (10) | 39 ± 7 (10) |
Control (NE) | 9 ± 2 (8) | 49 ± 8 (8) | 15 ± 5 (8) | 83 ± 2 (8) | 55 ± 11 (8) |
NE | 26 ± 4 (8)* | 81 ± 5 (8)* | 47 ± 3 (8)* | 59 ± 5 (8)* | 5 ± 2 (8)* |
Glt | |||||
Control | 26 ± 3 (8) | 160 ± 20 (10) | 140 ± 20 (10) | 18 ± 5 (10) | 0.6 ± 0.2 (10) |
Apamin | 37 ± 16 (8)* | 170 ± 20 (10) | 150 ± 20 (10) | 26 ± 5 (10) | 0.5 ± 0.1 (10) |
Control (NE) | 23 ± 2 (9) | 150 ± 7 (9) | 120 ± 10 (9) | 17 ± 3 (9) | 0.6 ± 0.2 (9) |
NE | 24 ± 2 (9) | 160 ± 7 (9) | 130 ± 7 (9) | 23 ± 5 (9) | 0.7 ± 0.2 (9) |
Data are presented as means ± SE (n, number of cells). Firing was elicited in response to 2-s current injections at different amplitudes. Firing rate (2 s) is the average firing frequency over the entire 2-s current injection (in Hz). Percentage of adaptation = 100 × (frequency at 3rd ISI - frequency at steady state ISI/frequency at 3rd ISI). Adaptation index was for firing at 3× rheobase.
-
↵* Significant difference vs. control (P < 0.05, paired t-test). NE, norepinephrine.
Inferred neuron-electrophysiology data values
Neuron Type | Neuron Description | Ephys Prop | Extracted Value | Standardized Value | Content Source |
---|