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Article: Synaptic mechanisms underlying thalamic activation-induced plasticity in the rat auditory cortex.

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Zhu ZR; Xu F; Ji WG; Ren SC; Chen F; Chen PZ; Jiang HH; Mi Z; Hu B; Zhang J; Xiong Y
J. Neurophysiol., 2014


Table 3.

Summary of four types of plasticity and their pharmacological profiles

LTPlongLTPshortLTDrLTDs
n7757
Amplitude*2.43 ± 0.321.77 ± 0.300.44 ± 0.080.63 ± 0.12
Slope*4.29 ± 0.300.35 ± 0.321.81 ± 0.10.01 ± 0
Recovery time, min22.12 ± 3.0825.03 ± 4.79
Pharmacological profileAPV+APV+APV-MPEP-
BIC+MPEP+APV+
AM251+BIC+
  • Parameter values are means ± SE for n cells sampled. Amplitude, amplitude of LTP (LTD); slope, slope of LTP (LTD) as measured at half-amplitude of LTP (LTD); recovery time, time required for excitatory postsynaptic current (EPSC) to recover from LTD/LTP to 85% of its amplitude; +, had an effect on LTP (LTD); -, had no effect on LTP (LTD); BIC, bicuculline.

  • * P < 0.05 (1-way ANOVA).


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Neuron Type Neuron Description Ephys Prop Extracted Value Standardized Value Content Source