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Article: Activation of InsP₃ receptors is sufficient for inducing graded intrinsic plasticity in rat hippocampal pyramidal neurons.
Full Text (publisher's website) ; Article Metadata ; Article Data (extracted) Ashhad S; Johnston D; Narayanan R J. Neurophysiol., 2015
Table 1.
Measurements sensitive to changes in HCN channels
| Measurement | Initial | 45 Min | P Value |
|---|---|---|---|
| RMP, mV | 60.9 ± 0.4 | 56.3 ± 1.3 | 3.4 × 10-3 |
| Rin, MΩ | 76.0 ± 5.0 | 49.5 ± 5.8 | 5.1 × 10-3 |
| Sag, % | 19.7 ± 2.2 | 22.9 ± 2.5 | 2.6 × 10-3 |
| fR, Hz | 4.13 ± 0.3 | 5.77 ± 0.4 | 6.9 × 10-4 |
| Q | 1.2 ± 0.05 | 1.4 ± 0.09 | 0.035 |
| |Z|max, MΩ | 80.6 ± 5.0 | 63.7 ± 4.6 | 8.9 × 10-5 |
| ΦL, rad·Hz | 0.04 ± 0.02 | 0.12 ± 0.05 | 0.024 |
| Sα | 1.14 ± 0.04 | 0.94 ± 0.05 | 1.4 × 10-3 |
Values are means ± SE of measurements sensitive to changes in HCN channels, determined at the beginning of (initial) and after 45 min of experiments where 10 μM inositol trisphosphate was included in the recording pipette. P values are reported for the paired Student's t-test. RMP, resting membrane potential; Rin, input resistance; fR, resonance frequency; Q, resonance strength; |Z|max, maximum impedance amplitude; ΦL, total inductive phase; and Sα, summation of α-excitatory postsynaptic potentials.
Inferred neuron-electrophysiology data values
| Neuron Type | Neuron Description | Ephys Prop | Extracted Value | Standardized Value | Content Source |
|---|---|---|---|---|---|
| Hippocampus CA1 pyramidal cell | sag ratio | 19.7 ± 2.2 | 0.197 (ratio) | Data Table | |
| Hippocampus CA1 pyramidal cell | firing frequency (Hz) | 4.13 ± 0.3 | 4.13 (Hz) | Data Table | |
| Hippocampus CA1 pyramidal cell | resting membrane potential (mV) | 60.9 ± 0.4 | -60.9 (mV) | Data Table | |
| Hippocampus CA1 pyramidal cell | input resistance (MΩ) | 76.0 ± 5.0 | 76.0 (MΩ) | Data Table |