Article: Examining protection from anoxic depolarization by the drugs dibucaine and carbetapentane using whole-cell recording from CA1 neurons.
Full Text (publisher's website) ;
Article Metadata ;
Article Data (extracted)
None
J. Neurophysiol., 2012
Table 4. Drug effects on the intrinsic properties of CA1 neurons
Control (n = 45) 3 μM Dib (n = 9) 10 μM CP (n = 12) 30 μM CP (n = 11) 100 μM CP (n = 5) 3 μM Dib and 30 μM CP (n = 11) RMP, mV -62.5 ± 3.0 -59.7 ± 3.0 -62.4 ± 3.2 -65.6 ± 3.1 -64.0 ± 2.6 -63.5 ± 3.7 fAHP, mV -3.4 ± 1.9 -2.7 ± 1.7 Absent* (11/12) Absent* Absent* Absent* AP threshold, mV -47.5 ± 4.4 -46.0 ± 3.8 -47.7 ± 2.7 -49.1 ± 2.8 -47.0 ± 3.4 -38.8 ± 4.6† AP freq (0.1 nA), Hz 12.7 ± 9.5 12.3 ± 9.5 6.8 ± 4.4 * 6.0 ± 2.1* 1.2 ± 1.3† 0.5 ± 0.8† AP freq (0.2 nA), Hz 24.3 ± 9.5 34.2 ± 16.4 13.2 ± 4.2† 9.4 ± 2.5† 1.6 ± 0.9† 2.3 ± 1.8† AP freq (0.3 nA), Hz 31.5 ± 8.7 N/A 16.8 ± 5.1† 11.4 ± 2.8† 2.2 ± 1.1† 2.9 ± 2.3† AP ampl, mV 89.6 ± 10.0 70 ± 21.5* 82.3 ± 14.4 74.9 ± 15.4* 62.5 ± 15.0† 70.5 ± 10.2* AP dur (½ ampl), ms 1.0 ± 0.1 1.0 ± 0.2 1.0 ± 0.1 1.4 ± 0.9* 2.0 ± 2.6† 1.3 ± 0.2* R in , MΩ47.4 ± 8.4 46.6 ± 1.7 45.8 ± 6.3 66.8 ± 17.2* 80.9 ± 16.9† 57.5 ± 11.5*
Inferred neuron-electrophysiology data values
Neuron Type
Neuron Description
Ephys Prop
Extracted Value
Standardized Value
Content Source