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Article: Differences in Dysfunction of Thenar and Hypothenar Motoneurons in Amyotrophic Lateral Sclerosis.

Full Text (publisher's website) ; Article Metadata ; Article Data (extracted)
Fang J; Cui L; Liu M; Guan Y; Li X; Li D; Cui B; Shen D; Ding Q
Front Hum Neurosci, 2016


Results of nerve conduction study.

Parameters Group 1 Group 2 NC P-value Group 1 vs. NC P-value Group 2 vs. NC P-value Groups 1 vs. 2
DML (ms)
APB 3.71 (0.78)* 3.17 (0.40)* 2.93 (0.41)* <0.001 0.028 <0.001
ADM 2.46 (0.46)* 2.29 (0.31)* 2.15 (0.29)* 0.002 0.142 0.301
CMAP amplitude (mV)
APB 2.85 (1.39)* 11.76 (2.84) 12.44 (3.21) <0.05 >0.05 <0.05
ADM 8.34 (2.58)* 13.25 (2.46) 13.76 (2.31) <0.05 >0.05 <0.05
ADM/APB ratio 3.74 (2.56) 1.12 (0.28) 1.12 (0.39) <0.001 0.620 <0.001
MCV (m/s)
APB 55.56 (5.78) 56.99 (5.58) 57.13 (5.98) >0.05 >0.05 >0.05
ADM 56.53 (6.87) 58.35 (6.78) 56.33 (3.51) >0.05 >0.05 >0.05

ADM, abductor digiti minimi; ALS, amyotrophic lateral sclerosis; APB, abductor pollicis brevis; ADM/APB ratio, ADM/APB CMAP amplitude ratio; CMAP, compound muscle action potential; DML, distal motor latency; MCV, motor conduction velocity; NC, normal control. All data are expressed as mean (SD). Values with significant differences printed in bold characters. *P < 0.001, between the APB and the ADM in each group. For comparisons of DML and ADM/APB ratio between the ALS patients in groups 1 and 2, and the normal controls, Bonferroni correction with a level of significance of <0.017 was used.


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Inferred neuron-electrophysiology data values

Neuron Type Neuron Description Ephys Prop Extracted Value Standardized Value Content Source