Article: Differences in Dysfunction of Thenar and Hypothenar Motoneurons in Amyotrophic Lateral Sclerosis.
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Fang J; Cui L; Liu M; Guan Y; Li X; Li D; Cui B; Shen D; Ding Q
Front Hum Neurosci, 2016
Diagnostic performance of F-wave in amyotrophic lateral sclerosis (ALS) vs. normal controls (NCs).
| Parameters |
Cut-off value |
Sensitivity (%) |
Specificity (%) |
AUC (95% CI) |
| APB |
| Minimal F latency |
24.55 ms |
60.0 |
75.0 |
0.646 (0.505–0.787) P = 0.068 |
| Maximal F latency |
28.30 ms |
70.0 |
75.0 |
0.792 (0.678–0.906) P < 0.001 |
| Mean F amplitude |
260.00 μV |
62.5 |
55.0 |
0.526 (0.393–0.656) P = 0.738 |
| F/M amplitude ratio |
2.60 |
72.5 |
85.0 |
0.820 (0.699–0.907) P < 0.001 |
| F persistence |
81.00% |
95.0 |
100.0 |
0.976 (0.898–0.998) P < 0.001 |
| Index RN |
9.64% |
97.5 |
100.0 |
0.998 (0.937–1.000) P < 0.001 |
| Index Freps |
19.35% |
100.0 |
100.0 |
1.000 (0.940–1.000) P < 0.001 |
| ADM |
| Minimal F latency |
22.80 ms |
92.5 |
35.0 |
0.664 (0.530–0.781) P = 0.034 |
| Maximal F latency |
26.70 ms |
85.0 |
65.0 |
0.769 (0.642–0.868) P < 0.001 |
| Mean F latency |
26.70 ms |
65.0 |
70.0 |
0.695 (0.563–0.807) P = 0.011 |
| Mean F amplitude |
320.00 μV |
57.5 |
85.0 |
0.716 (0.585–0.825) P = 0.001 |
| F/M amplitude ratio |
2.66 |
62.5 |
90.0 |
0.819 (0.699–0.907) P < 0.001 |
| F persistence |
97.00% |
55.0 |
95.0 |
0.750 (0.621–0.853) P < 0.001 |
| Index RN |
0.00% |
75.0 |
80.0 |
0.804 (0.681–0.895) P < 0.001 |
| Index Freps |
0.00% |
75.0 |
80.0 |
0.805 (0.682–0.896) P < 0.001 |
APB, abductor pollicis brevis; ADM, abductor digiti minimi; AUC, area under the curve; CI, confidence interval.
Inferred neuron-electrophysiology data values
| Neuron Type |
Neuron Description |
Ephys Prop |
Extracted Value |
Standardized Value |
Content Source |
