NeuroElectro Publications

Article: Anti-GAD65 Containing Cerebrospinal Fluid Does not Alter GABAergic Transmission.

Full Text (publisher's website) ; Article Metadata ; Article Data (extracted)
Hackert JK; Müller L; Rohde M; Bien CG; Köhling R; Kirschstein T
Front Cell Neurosci, 2016

Table 1

CA1 pyramidal cell properties (intracellular recordings).

Cell property	Control (n = 9)	Anti-GAD (n = 8)	P value
Resting membrane potential	-68 ± 1 mV	-67 ± 1 mV	0.72
Membrane resistance	44 ± 4 MΩ	55 ± 4 MΩ	0.07
Time constant	11.8 ± 0.5 ms	12.6 ± 0.9 ms	0.47
Voltage sag (injection of -1.0 nA)	-5.1 ± 0.9 mV	-7.4 ± 0.9 mV	0.12
AHP (injection of 0.5 nA)	-5.6 ± 0.9 mV	-6.4 ± 1.0 mV	0.57
AP number (injection of 0.5 nA)	5.1 ± 0.6	6.2 ± 0.8	0.28

Inferred neuron-electrophysiology data values

Neuron Type	Neuron Description	Ephys Prop	Extracted Value	Standardized Value	Content Source
Hippocampus CA1 pyramidal cell	hippocampus CA1 pyramidal GABAergic cell	membrane time constant	11.8 ± 0.5 (9)	11.8 (ms)	Data Table
Hippocampus CA1 pyramidal cell	hippocampus CA1 pyramidal GABAergic cell	sag amplitude	-5.1 ± 0.9 (9)	-5.1 (mV)	Data Table
Hippocampus CA1 pyramidal cell	hippocampus CA1 pyramidal GABAergic cell	AHP amplitude	-5.6 ± 0.9 (9)	5.6 (mV)	Data Table
Hippocampus CA1 pyramidal cell	hippocampus CA1 pyramidal GABAergic cell	resting membrane potential	-68.0 ± 1.0 (9)	-68.0 (mV)	Data Table
Hippocampus CA1 pyramidal cell	hippocampus CA1 pyramidal GABAergic cell	input resistance	44.0 ± 4.0 (9)	44.0 (MΩ)	Data Table