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Article: Activation of Pyramidal Neurons in Mouse Medial Prefrontal Cortex Enhances Food-Seeking Behavior While Reducing Impulsivity in the Absence of an Effect on Food Intake.

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Warthen DM; Lambeth PS; Ottolini M; Shi Y; Barker BS; Gaykema RP; Newmyer BA; Joy-Gaba J; Ohmura Y; Perez-Reyes E; Güler AD; Patel MK; Scott MM
Front Behav Neurosci, 2016


Nosepokes into inactive ports during progressive ratio (PR) testing on ad lib feeding.

Saline CNO 0.5 mg/kg
N Pokes σ N Pokes σ
FR5 16 3.5 3.2 16 2.5 2.76
FR10 16 1.88 2.42 16 1.31 1.3
FR20 16 2.69 4.33 16 3.25 2.57
FR30 16 4.31 4.81 16 4.56 4.95
FR50 10 11.6 12 13 6.54 4.52
FR70 5 13.8 13.7 8 9.5 7.01
FR100 1 5 N/A 4 12.75 8.46
FR130 0 N/A N/A 1 5 N/A

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Inferred neuron-electrophysiology data values

Neuron Type Neuron Description Ephys Prop Extracted Value Standardized Value Content Source