Article: TWIK-1 contributes to the intrinsic excitability of dentate granule cells in mouse hippocampus.

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Yarishkin O; Lee da Y; Kim E; Cho CH; Choi JH; Lee CJ; Hwang EM; Park JY
Mol Brain, 2014

Table S1: Membrane electrical properties of dentate granule cells
	Naive (n=36)	Sc shRNA (n=32)	TWIK-1 shRNA (n=30)
Resting membrane potential (mV)	-74.9 +/- 0.6	-77.3 +/- 1.2	-70.6 +/- 0.6*
Input resistance (MOhm)	185.8 +/- 7.2	213.8 +/- 9.5	231.78 +/-9.8
Firing threshold potential (mV)	-37.2 +/- 0.7	-38.3 +/- 1.0	-39.3 +/- 0.7
Number of Spikes (at 30pA)	1.7 +/- 0.6	1.9 +/- 0.5	7.2 +/- 1.0*
AP Amplitude (mV)	77.5 +/- 1.8	75.1 +/- 1.7	73.5 +/- 1.5
Rheobase Current (pA)	42.4	42.8	26.4*
Data included from Rheobase measurements from Figure 3 regarding intrinsic excitability. Data are expressed as mean ± S.E.M (naïve, n=36; ScshRNA, n=32; TWIK-1 shRNA,n = 30). P values were calculated using the Student’s unpaired or paired t-test. * indicates P

Inferred neuron-electrophysiology data values

Neuron Type	Ephys Prop	Extracted Value	Standardized Value	Content Source
Dentate gyrus granule cell	spike threshold (mV)	-37.2 ± 0.7 (36)	-37.2 (mV)	Data Table
Dentate gyrus granule cell	spike amplitude (mV)	77.5 ± 1.8 (36)	77.5 (mV)	Data Table
Dentate gyrus granule cell	resting membrane potential (mV)	-74.9 ± 0.6 (36)	-74.9 (mV)	Data Table
Dentate gyrus granule cell	rheobase (pA)	42.4 (36)	42.4 (pA)	Data Table
Dentate gyrus granule cell	input resistance	185.8 ± 7.2 (36)	185.8 (MΩ)	Data Table